(S)-[(3R,5S)-5-(benzyloxy)oct-1-en-3-yl] 3-[4-(2-(benzyloxy)ethoxy)phenyl]-2-[tert-butoxycarbonyl(methyl)amino]propanoate

Base Information

Chemical Name:(S)-[(3R,5S)-5-(benzyloxy)oct-1-en-3-yl] 3-[4-(2-(benzyloxy)ethoxy)phenyl]-2-[tert-butoxycarbonyl(methyl)amino]propanoate
CAS No.:1388220-69-6
Molecular Formula:C₃₉H₅₁NO₇
Molecular Weight:645.836
Hs Code.:

Synonyms:(S)-[(3R,5S)-5-(benzyloxy)oct-1-en-3-yl] 3-[4-(2-(benzyloxy)ethoxy)phenyl]-2-[tert-butoxycarbonyl(methyl)amino]propanoate

Suppliers and Price of (S)-[(3R,5S)-5-(benzyloxy)oct-1-en-3-yl] 3-[4-(2-(benzyloxy)ethoxy)phenyl]-2-[tert-butoxycarbonyl(methyl)amino]propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-[(3R,5S)-5-(benzyloxy)oct-1-en-3-yl] 3-[4-(2-(benzyloxy)ethoxy)phenyl]-2-[tert-butoxycarbonyl(methyl)amino]propanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-[(3R,5S)-5-(benzyloxy)oct-1-en-3-yl] 3-[4-(2-(benzyloxy)ethoxy)phenyl]-2-[tert-butoxycarbonyl(methyl)amino]propanoate

There total 7 articles about (S)-[(3R,5S)-5-(benzyloxy)oct-1-en-3-yl] 3-[4-(2-(benzyloxy)ethoxy)phenyl]-2-[tert-butoxycarbonyl(methyl)amino]propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1388220-71-0
(3R,5S)-5-(benzyloxy)oct-1-en-3-ol

: (S)-3-(4-(2-(benzyloxy)ethoxy)phenyl)-2-(tert-butoxycarbonyl(methyl)amino)propanoic acid

: 1388220-69-6
(S)-[(3R,5S)-5-(benzyloxy)oct-1-en-3-yl] 3-[4-(2-(benzyloxy)ethoxy)phenyl]-2-[tert-butoxycarbonyl(methyl)amino]propanoate

Guidance literature:: With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 0 - 20 ℃; for 12h; Inert atmosphere;
DOI:10.1016/j.tetasy.2012.05.013

Reference yield:

: 1035455-07-2
C₁₃H₁₈O₂

: 1388220-69-6
(S)-[(3R,5S)-5-(benzyloxy)oct-1-en-3-yl] 3-[4-(2-(benzyloxy)ethoxy)phenyl]-2-[tert-butoxycarbonyl(methyl)amino]propanoate

Guidance literature:: Multi-step reaction with 3 steps

1.1: tetrahydrofuran / 1 h / -20 °C / Inert atmosphere

1.2: Inert atmosphere

2.1: titanium(IV) isopropylate; L-(+)-diisopropyl tartrate; Cumene hydroperoxide / dichloromethane / 12 h / -20 - 0 °C / Inert atmosphere; Molecular sieve

3.1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 12 h / 0 - 20 °C / Inert atmosphere

With titanium(IV) isopropylate; dmap; L-(+)-diisopropyl tartrate; Cumene hydroperoxide; dicyclohexyl-carbodiimide; In tetrahydrofuran; dichloromethane; 2.1: Sharpless kinetic resolution;
DOI:10.1016/j.tetasy.2012.05.013

Reference yield:

: 1388220-73-2
(S)-methyl 2-[tert-butoxycarbonyl(methyl)amino]-3-[4-(2-hydroxyethoxy)phenyl]propanoate

: 1388220-69-6
(S)-[(3R,5S)-5-(benzyloxy)oct-1-en-3-yl] 3-[4-(2-(benzyloxy)ethoxy)phenyl]-2-[tert-butoxycarbonyl(methyl)amino]propanoate

Guidance literature:: Multi-step reaction with 3 steps

1: silver(l) oxide / N,N-dimethyl-formamide / 12 h / 20 °C / Inert atmosphere

2: lithium hydroxide / tetrahydrofuran; methanol; water / 6 h / 0 - 20 °C / Inert atmosphere

3: dmap; dicyclohexyl-carbodiimide / dichloromethane / 12 h / 0 - 20 °C / Inert atmosphere

With dmap; dicyclohexyl-carbodiimide; silver(l) oxide; lithium hydroxide; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/j.tetasy.2012.05.013