1β-(m-iodo)benzyl-hepta-O-acetyl cellobioside

Base Information

• Chemical Name: 1β-(m-iodo)benzyl-hepta-O-acetyl cellobioside
• CAS No.: 1252764-11-6
• Molecular Formula: C₃₃H₄₁IO₁₈
• Molecular Weight: 852.582
• Mol file: 1252764-11-6.mol

Synonyms:1β-(m-iodo)benzyl-hepta-O-acetyl cellobioside

Chemical Property of 1β-(m-iodo)benzyl-hepta-O-acetyl cellobioside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1β-(m-iodo)benzyl-hepta-O-acetyl cellobioside

There total 2 articles about 1β-(m-iodo)benzyl-hepta-O-acetyl cellobioside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

3-iodobenzylalcohol (57455-06-8) + 4-O-(2',3',4',6'-tetra-O-acetyl-β-D-glucopyranosyl)-2,3,6-tri-O-acetyl-α-D-glucopyranosyl trichloracetimidate (92052-38-5,106256-81-9,106256-89-7,126736-02-5,132287-70-8,132287-71-9,139403-73-9,130703-21-8) → 1β-(m-iodo)benzyl-hepta-O-acetyl cellobioside (1252764-11-6)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; at -15 ℃; for 1h; Inert atmosphere; Molecular sieve;

DOI:10.1080/07328303.2010.508142

Reference yield:

β-cellobioseoctaacetate (20764-63-0) → 1β-(m-iodo)benzyl-hepta-O-acetyl cellobioside (1252764-11-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: hydrazine / N,N-dimethyl-formamide / 50 °C / Inert atmosphere

1.2: 1 h / 20 °C / Inert atmosphere

2.1: boron trifluoride diethyl etherate / dichloromethane / 1 h / -15 °C / Inert atmosphere; Molecular sieve

With boron trifluoride diethyl etherate; hydrazine; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1080/07328303.2010.508142

Reference yield: 100.0%

1β-(m-iodo)benzyl-hepta-O-acetyl cellobioside (1252764-11-6) → 1β-(m-iodo)benzyl cellobioside (1252764-12-7)

Guidance literature:

With methanol; sodium methylate; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1080/07328303.2010.508142

upstream raw materials:

3-iodobenzylalcohol

4-O-(2',3',4',6'-tetra-O-acetyl-β-D-glucopyranosyl)-2,3,6-tri-O-acetyl-α-D-glucopyranosyl trichloracetimidate

β-cellobioseoctaacetate

Downstream raw materials:

1β-(m-iodo)benzyl cellobioside

Refernces