C₁₂H₁₉NO₃

Base Information

• Chemical Name: C₁₂H₁₉NO₃
• CAS No.: 1393110-49-0
• Molecular Formula: C₁₂H₁₉NO₃
• Molecular Weight: 225.288
• Mol file: 1393110-49-0.mol

Synonyms:C₁₂H₁₉NO₃

Chemical Property of C₁₂H₁₉NO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of C₁₂H₁₉NO₃

There total 1 articles about C₁₂H₁₉NO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

tert-butyl carbazate (4248-19-5) + C8H9F3O4S (1393110-52-5) → C12H19NO3 (1393110-49-0)

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; potassium carbonate; tert-butyl XPhos; In toluene; at 80 ℃; for 9h; Reagent/catalyst; Inert atmosphere;

DOI:10.1021/ol301951r

Reference yield: 83.0%

C12H19NO3 (1393110-49-0) + 2-(bromomethyl)-3-bromo-6-methoxypyridine (156094-64-3) → C19H25BrN2O4 (1391436-01-3)

Guidance literature:

With 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; lithium diisopropyl amide; In tetrahydrofuran; at -50 - 10 ℃; diastereoselective reaction;

DOI:10.1007/s11426-011-4480-y

Reference yield:

C12H19NO3 (1393110-49-0) → C24H33BrN2O6 (1393110-47-8)

Guidance literature:

Multi-step reaction with 2 steps

1: dmap

2: 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; lithium diisopropyl amide / tetrahydrofuran

With dmap; 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; lithium diisopropyl amide; In tetrahydrofuran;

DOI:10.1007/s11426-011-4480-y

upstream raw materials:

tert-butyl carbazate

C₈H₉F₃O₄S

Downstream raw materials:

C₂₄H₃₃BrN₂O₆

C₂₁H₃₁BrN₂O₄

C₂₁H₃₁BrN₂O₄

C₁₉H₂₅BrN₂O₄