4-oxo-2-thioxo-3-p-tolyl-1,2,3,4,5,6-hexahydrospiro(benzo[h]quinazoline-5,1'-cyclopentane)

Base Information

• Chemical Name: 4-oxo-2-thioxo-3-p-tolyl-1,2,3,4,5,6-hexahydrospiro(benzo[h]quinazoline-5,1'-cyclopentane)
• CAS No.: 287491-49-0
• Molecular Formula: C₂₃H₂₂N₂OS
• Molecular Weight: 374.506

Synonyms:4-oxo-2-thioxo-3-p-tolyl-1,2,3,4,5,6-hexahydrospiro(benzo[h]quinazoline-5,1'-cyclopentane)

Chemical Property of 4-oxo-2-thioxo-3-p-tolyl-1,2,3,4,5,6-hexahydrospiro(benzo[h]quinazoline-5,1'-cyclopentane)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-oxo-2-thioxo-3-p-tolyl-1,2,3,4,5,6-hexahydrospiro(benzo[h]quinazoline-5,1'-cyclopentane)

There total 1 articles about 4-oxo-2-thioxo-3-p-tolyl-1,2,3,4,5,6-hexahydrospiro(benzo[h]quinazoline-5,1'-cyclopentane) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

1-isothiocyanato-4-methylbenzene (622-59-3) + 4-amino-3-ethoxycarbonyl-1,2-dihydrospiro(naphthalene-2,1'-cyclopentane) (221238-51-3) → 4-oxo-2-thioxo-3-p-tolyl-1,2,3,4,5,6-hexahydrospiro(benzo[h]quinazoline-5,1'-cyclopentane) (287491-49-0)

Guidance literature:

1-isothiocyanato-4-methylbenzene; 4-amino-3-ethoxycarbonyl-1,2-dihydrospiro(naphthalene-2,1'-cyclopentane); In ethanol; for 14h; Heating;

With potassium hydroxide; In ethanol; for 5h; Heating;

DOI:10.1007/BF02251821

Reference yield: 90.0%

4-oxo-2-thioxo-3-p-tolyl-1,2,3,4,5,6-hexahydrospiro(benzo[h]quinazoline-5,1'-cyclopentane) (287491-49-0) → 2-hydrazino-4-oxo-3-p-tolyl-3,4,5,6-tetrahydrospiro(benzo[h]quinazoline-5,1'-cyclopentane) (287491-51-4)

Guidance literature:

With hydrazine hydrate; In butan-1-ol; for 20h; Heating;

DOI:10.1007/BF02252007

Reference yield: 75.0%

4-oxo-2-thioxo-3-p-tolyl-1,2,3,4,5,6-hexahydrospiro(benzo[h]quinazoline-5,1'-cyclopentane) (287491-49-0) → C24H24N2OS

Guidance literature:

With potassium hydroxide; In ethanol; for 8h; Heating;

DOI:10.1007/BF02251821

upstream raw materials:

1-isothiocyanato-4-methylbenzene

4-amino-3-ethoxycarbonyl-1,2-dihydrospiro(naphthalene-2,1'-cyclopentane)

Downstream raw materials:

2-hydrazino-4-oxo-3-p-tolyl-3,4,5,6-tetrahydrospiro(benzo[h]quinazoline-5,1'-cyclopentane)

C₂₇H₂₈N₂O₃S

C₂₅H₂₆N₂OS

C₂₇H₃₀N₂OS

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 287491-49-0 4-oxo-2-thioxo-3-p-tolyl-1,2,3,4,5,6-hexahydrospiro(benzo[h]quinazoline-5,1'-cyclopentane)

Send

Send

Metric Ton KG G Pound L ML

Send

Send