2-hydrazino-4-oxo-3-p-tolyl-3,4,5,6-tetrahydrospiro(benzo[h]quinazoline-5,1'-cyclopentane)

Base Information

• Chemical Name: 2-hydrazino-4-oxo-3-p-tolyl-3,4,5,6-tetrahydrospiro(benzo[h]quinazoline-5,1'-cyclopentane)
• CAS No.: 287491-51-4
• Molecular Formula: C₂₃H₂₄N₄O
• Molecular Weight: 372.47
• Mol file: 287491-51-4.mol

Synonyms:2-hydrazino-4-oxo-3-p-tolyl-3,4,5,6-tetrahydrospiro(benzo[h]quinazoline-5,1'-cyclopentane)

Chemical Property of 2-hydrazino-4-oxo-3-p-tolyl-3,4,5,6-tetrahydrospiro(benzo[h]quinazoline-5,1'-cyclopentane)

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 2-hydrazino-4-oxo-3-p-tolyl-3,4,5,6-tetrahydrospiro(benzo[h]quinazoline-5,1'-cyclopentane)

There total 1 articles about 2-hydrazino-4-oxo-3-p-tolyl-3,4,5,6-tetrahydrospiro(benzo[h]quinazoline-5,1'-cyclopentane) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-oxo-2-thioxo-3-p-tolyl-1,2,3,4,5,6-hexahydrospiro(benzo[h]quinazoline-5,1'-cyclopentane) (287491-49-0) → 2-hydrazino-4-oxo-3-p-tolyl-3,4,5,6-tetrahydrospiro(benzo[h]quinazoline-5,1'-cyclopentane) (287491-51-4)

Guidance literature:

With hydrazine hydrate; In butan-1-ol; for 20h; Heating;

DOI:10.1007/BF02252007

Reference yield: 84.0%

orthoformic acid triethyl ester (122-51-0) + 2-hydrazino-4-oxo-3-p-tolyl-3,4,5,6-tetrahydrospiro(benzo[h]quinazoline-5,1'-cyclopentane) (287491-51-4) → C24H22N4O

Guidance literature:

In butan-1-ol; for 6h; Heating;

DOI:10.1007/BF02252007

Reference yield: 81.0%

2-hydrazino-4-oxo-3-p-tolyl-3,4,5,6-tetrahydrospiro(benzo[h]quinazoline-5,1'-cyclopentane) (287491-51-4) → C23H21N5O

Guidance literature:

With acetic acid; sodium nitrite; In water; at 20 ℃; for 0.5h;

DOI:10.1007/BF02252007

upstream raw materials:

4-oxo-2-thioxo-3-p-tolyl-1,2,3,4,5,6-hexahydrospiro(benzo[h]quinazoline-5,1'-cyclopentane)