acetic acid 1-[3-(2-chlorophenyl)-5-methylisoxazol-4-yl]-2-cyanoallyl ester

Base Information

Chemical Name:acetic acid 1-[3-(2-chlorophenyl)-5-methylisoxazol-4-yl]-2-cyanoallyl ester
CAS No.:635681-06-0
Molecular Formula:C₁₆H₁₃ClN₂O₃
Molecular Weight:316.744
Hs Code.:

Synonyms:acetic acid 1-[3-(2-chlorophenyl)-5-methylisoxazol-4-yl]-2-cyanoallyl ester

Suppliers and Price of acetic acid 1-[3-(2-chlorophenyl)-5-methylisoxazol-4-yl]-2-cyanoallyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of acetic acid 1-[3-(2-chlorophenyl)-5-methylisoxazol-4-yl]-2-cyanoallyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of acetic acid 1-[3-(2-chlorophenyl)-5-methylisoxazol-4-yl]-2-cyanoallyl ester

There total 5 articles about acetic acid 1-[3-(2-chlorophenyl)-5-methylisoxazol-4-yl]-2-cyanoallyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 75-36-5
acetyl chloride

: 635680-61-4
2-{[3-(2-chlorophenyl)-5-methylisoxazol-4-yl]hydroxymethyl}acrylonitrile

: 635681-06-0
acetic acid 1-[3-(2-chlorophenyl)-5-methylisoxazol-4-yl]-2-cyanoallyl ester

Guidance literature:: With pyridine; In dichloromethane; at 20 ℃; for 1h;
DOI:10.1055/s-2003-40204

Reference yield:

: 4357-94-2
methyl 3-(2'-chlorophenyl)-5-methylisoxazole-4-carboxylate

: 635681-06-0
acetic acid 1-[3-(2-chlorophenyl)-5-methylisoxazol-4-yl]-2-cyanoallyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 100 percent / LiAlH₄ / diethyl ether / 1 h / 40 °C

2: PCC / CH₂Cl₂ / 0.5 h / 20 °C

3: 79 percent / DABCO / 72 h / 20 °C

4: 88 percent / pyridine / CH₂Cl₂ / 1 h / 20 °C

With pyridine; 1,4-diaza-bicyclo[2.2.2]octane; lithium aluminium tetrahydride; pyridinium chlorochromate; In diethyl ether; dichloromethane; 3: Baylis-Hillman reaction;
DOI:10.1055/s-2003-40204

Reference yield:

: 29568-74-9
2-chloro-N-hydroxybenzimidoyl chloride

: 635681-06-0
acetic acid 1-[3-(2-chlorophenyl)-5-methylisoxazol-4-yl]-2-cyanoallyl ester

Guidance literature:: Multi-step reaction with 5 steps

1.1: NaOMe / methanol

1.2: methanol / 4 h / 0 °C

2.1: 100 percent / LiAlH₄ / diethyl ether / 1 h / 40 °C

3.1: PCC / CH₂Cl₂ / 0.5 h / 20 °C

4.1: 79 percent / DABCO / 72 h / 20 °C

5.1: 88 percent / pyridine / CH₂Cl₂ / 1 h / 20 °C

With pyridine; 1,4-diaza-bicyclo[2.2.2]octane; lithium aluminium tetrahydride; sodium methylate; pyridinium chlorochromate; In methanol; diethyl ether; dichloromethane; 4.1: Baylis-Hillman reaction;
DOI:10.1055/s-2003-40204