Bicyclo[2.2.1]heptane-2,6-dicarboxaldehyde, (2R,6S)-rel- (9CI)

Base Information

• Chemical Name: Bicyclo[2.2.1]heptane-2,6-dicarboxaldehyde, (2R,6S)-rel- (9CI)
• CAS No.: 346611-50-5
• Molecular Formula: C₉H₁₂O₂
• Molecular Weight: 152.193
• Mol file: 346611-50-5.mol

Synonyms:Bicyclo[2.2.1]heptane-2,6-dicarboxaldehyde, (2R,6S)-rel- (9CI)

Chemical Property of Bicyclo[2.2.1]heptane-2,6-dicarboxaldehyde, (2R,6S)-rel- (9CI)

Chemical Property:

• PSA: 34.14000
• LogP: 1.04650

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Bicyclo[2.2.1]heptane-2,6-dicarboxaldehyde, (2R,6S)-rel- (9CI)

There total 5 articles about Bicyclo[2.2.1]heptane-2,6-dicarboxaldehyde, (2R,6S)-rel- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

carbon monoxide (201230-82-2) + bicyclo[2.2.1]hepta-2,5-diene (121-46-0) → 5-Norbornene-2-carboxaldehyde (5453-80-5,19926-90-0) + 2,5-bisformylbicyclo[2.2.1]heptane + 2,6-bisformylbicyclo[2.2.1]heptane (346611-50-5)

Guidance literature:

With carbon dioxide; (R,S)-3-H²F⁶-BINAPHOS; hydrogen; bis(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; at 40 ℃; for 14h; under 128260 Torr;

DOI:10.1016/S0022-328X(00)00778-6

Reference yield:

carbon monoxide (201230-82-2) + 5-norbornene-2-carboxaldehyde → 2,6-norbornanedicarbaldehyde (346611-50-5) + 2,5-norbornanedicarbaldehyde

Guidance literature:

With hydrogen; dicarbonylacetylacetonato rhodium (I); In toluene; at 120 ℃; for 14h; under 15001.5 - 450045 Torr;

Reference yield:

5-Norbornene-2-carboxaldehyde (5453-80-5,19926-90-0) + carbon monoxide (201230-82-2) → 2,5-bisformylbicyclo[2.2.1]heptane + 2,6-bisformylbicyclo[2.2.1]heptane (346611-50-5)

Guidance literature:

With triphenyl phosphite; dicarbonylacetylacetonato rhodium (I); hydrogen; In toluene; at 25 - 100 ℃; for 6h; under 4500.45 Torr; Overall yield = 266.1 g; Autoclave; Inert atmosphere;

upstream raw materials:

carbon monoxide

bicyclo[2.2.1]hepta-2,5-diene

5-Norbornene-2-carboxaldehyde

bicyclo[2.2.1]hepta-2,5-diene