3-(tert-butyldimethylsilanyloxy)-2-(S)-(9H-fluoren-9-ylmethoxycarbonylamino)-thiopropionic acid S-phenyl ester

Base Information

Chemical Name:3-(tert-butyldimethylsilanyloxy)-2-(S)-(9H-fluoren-9-ylmethoxycarbonylamino)-thiopropionic acid S-phenyl ester
CAS No.:947325-54-4
Molecular Formula:C₃₀H₃₅NO₄SSi
Molecular Weight:533.764
Hs Code.:

Synonyms:3-(tert-butyldimethylsilanyloxy)-2-(S)-(9H-fluoren-9-ylmethoxycarbonylamino)-thiopropionic acid S-phenyl ester

Suppliers and Price of 3-(tert-butyldimethylsilanyloxy)-2-(S)-(9H-fluoren-9-ylmethoxycarbonylamino)-thiopropionic acid S-phenyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-(tert-butyldimethylsilanyloxy)-2-(S)-(9H-fluoren-9-ylmethoxycarbonylamino)-thiopropionic acid S-phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-(tert-butyldimethylsilanyloxy)-2-(S)-(9H-fluoren-9-ylmethoxycarbonylamino)-thiopropionic acid S-phenyl ester

There total 3 articles about 3-(tert-butyldimethylsilanyloxy)-2-(S)-(9H-fluoren-9-ylmethoxycarbonylamino)-thiopropionic acid S-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 18162-48-6
tert-butyldimethylsilyl chloride

: 428821-03-8
2-(S)-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxythiopropionic acid S-phenyl ester

: 947325-54-4
3-(tert-butyldimethylsilanyloxy)-2-(S)-(9H-fluoren-9-ylmethoxycarbonylamino)-thiopropionic acid S-phenyl ester

Guidance literature:: With 4-methyl-morpholine; dmap; In dichloromethane; at 20 ℃; for 3 - 24h;

Reference yield:

: 73724-45-5
N-(9H-fluoren-9-ylmethoxycarbonyl)-L-serine

: 947325-54-4
3-(tert-butyldimethylsilanyloxy)-2-(S)-(9H-fluoren-9-ylmethoxycarbonylamino)-thiopropionic acid S-phenyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / HOBt; DCC / ethyl acetate / 16 h / 20 °C

2: 36 percent / DMAP; N-methylmorpholine / dimethylformamide / 0.5 h / 20 °C

With 4-methyl-morpholine; dmap; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/ol070991m

Reference yield:

: 108-98-5
thiophenol

: 947325-54-4
3-(tert-butyldimethylsilanyloxy)-2-(S)-(9H-fluoren-9-ylmethoxycarbonylamino)-thiopropionic acid S-phenyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / HOBt; DCC / ethyl acetate / 16 h / 20 °C

2: 36 percent / DMAP; N-methylmorpholine / dimethylformamide / 0.5 h / 20 °C

With 4-methyl-morpholine; dmap; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/ol070991m