3-{3-[3-(2-hydroxy-ethylsulfanyl)-4-trifluoromethyl-phenyl]-5-methanesulfonyl-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl}propionaldehyde

Base Information

Chemical Name:3-{3-[3-(2-hydroxy-ethylsulfanyl)-4-trifluoromethyl-phenyl]-5-methanesulfonyl-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl}propionaldehyde
CAS No.:1049103-03-8
Molecular Formula:C₁₉H₂₂F₃N₃O₄S₂
Molecular Weight:477.529
Hs Code.:

Synonyms:3-{3-[3-(2-hydroxy-ethylsulfanyl)-4-trifluoromethyl-phenyl]-5-methanesulfonyl-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl}propionaldehyde

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Chemical Property of 3-{3-[3-(2-hydroxy-ethylsulfanyl)-4-trifluoromethyl-phenyl]-5-methanesulfonyl-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl}propionaldehyde

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Technology Process of 3-{3-[3-(2-hydroxy-ethylsulfanyl)-4-trifluoromethyl-phenyl]-5-methanesulfonyl-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl}propionaldehyde

There total 1 articles about 3-{3-[3-(2-hydroxy-ethylsulfanyl)-4-trifluoromethyl-phenyl]-5-methanesulfonyl-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl}propionaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1049103-02-7
2-{5-[1-(2-[1,3]dioxolan-2-yl-ethyl)-5-methanesulfonyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl]-2-trifluoromethyl-phenylsulfanyl}-ethanol

: 1049103-03-8
3-{3-[3-(2-hydroxy-ethylsulfanyl)-4-trifluoromethyl-phenyl]-5-methanesulfonyl-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl}propionaldehyde

Guidance literature:: With hydrogenchloride; water; In acetone; at 55 ℃;

Reference yield: 53.0%

: 1049103-03-8
3-{3-[3-(2-hydroxy-ethylsulfanyl)-4-trifluoromethyl-phenyl]-5-methanesulfonyl-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl}propionaldehyde

: 91596-61-1
1-(piperidin-4-yl)pyrrolidin-2-one

: 1049094-10-1
1-[1-(3-{3-[3-(2-hydroxy-ethylsulfanyl)-4-trifluoromethyl-phenyl]-5-methanesulfonyl-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl}-propyl)-piperidin-4-yl]-pyrrolidin-2-one

Guidance literature:: 3-{3-[3-(2-hydroxy-ethylsulfanyl)-4-trifluoromethyl-phenyl]-5-methanesulfonyl-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl}propionaldehyde; 1-(piperidin-4-yl)pyrrolidin-2-one; With sodium tris(acetoxy)borohydride; acetic acid; In dichloromethane; at 20 ℃; for 15h;

With sodium hydroxide; water; In dichloromethane;