1-ethoxycarbonylamino-1-(2,5-dimethylphenyl)-2,2-dichloroethane

Base Information

• Chemical Name: 1-ethoxycarbonylamino-1-(2,5-dimethylphenyl)-2,2-dichloroethane
• CAS No.: 128042-16-0
• Molecular Formula: C₁₃H₁₇Cl₂NO₂
• Molecular Weight: 290.189
• Mol file: 128042-16-0.mol

Synonyms:1-ethoxycarbonylamino-1-(2,5-dimethylphenyl)-2,2-dichloroethane

Chemical Property of 1-ethoxycarbonylamino-1-(2,5-dimethylphenyl)-2,2-dichloroethane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-ethoxycarbonylamino-1-(2,5-dimethylphenyl)-2,2-dichloroethane

There total 2 articles about 1-ethoxycarbonylamino-1-(2,5-dimethylphenyl)-2,2-dichloroethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

1,1-dichloro-2,2-di(ethoxycarbonylamino)ethane (1509-56-4) + para-xylene (106-42-3) → 1-ethoxycarbonylamino-1-(2,5-dimethylphenyl)-2,2-dichloroethane (128042-16-0)

Guidance literature:

With sulfuric acid; at 15 - 20 ℃;

Reference yield:

1,1,1-trichloro-2,2-di(ethoxycarbonylamino)ethane (17528-34-6) → 1-ethoxycarbonylamino-1-(2,5-dimethylphenyl)-2,2-dichloroethane (128042-16-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / aluminium amalgam / aq. ethanol / Heating

2: 85 percent / conc. sulfuric acid / 15 - 20 °C

With aluminium amalgam; sulfuric acid; In ethanol;

Reference yield:

1-ethoxycarbonylamino-1-(2,5-dimethylphenyl)-2,2-dichloroethane (128042-16-0) → 2,5-dimethyl-mandelic acid (5766-40-5)

Guidance literature:

With sodium hydroxide; In 1,4-dioxane; at 95 - 100 ℃;

upstream raw materials:

1,1-dichloro-2,2-di(ethoxycarbonylamino)ethane

para-xylene

1,1,1-trichloro-2,2-di(ethoxycarbonylamino)ethane

Downstream raw materials:

2,5-dimethyl-mandelic acid

2-(2,2-Dichloro-1-isocyanato-ethyl)-1,4-dimethyl-benzene

N,N'-di<1-(2,5-dimethylphenyl)-2,2-dichloroethyl>urea