5766-40-5

Usage

Uses

Used in Pharmaceutical Industry:
2-(2,5-DIMETHYLPHENYL)-2-HYDROXYACETIC ACID is used as a medication for the treatment of gout, specifically to decrease uric acid levels in the body. This helps in preventing gout attacks and managing the associated symptoms. It is administered orally and is available in tablet form, with dosage and directions provided by healthcare professionals to ensure safe and effective treatment.
Common side effects associated with the use of 2-(2,5-DIMETHYLPHENYL)-2-HYDROXYACETIC ACID may include nausea, rash, and liver function abnormalities, which should be monitored and managed accordingly.

InChI:InChI=1/C10H12O3/c1-6-3-4-7(2)8(5-6)9(11)10(12)13/h3-5,9,11H,1-2H3,(H,12,13)

Upstream product

• 106-42-3 para-xylene 
• 609-09-6 Diethyl ketomalonate 
• 161236-68-6 4,4-Dimethyl-2-(4-methyl-benzyloxymethyl)-4,5-dihydro-oxazole 
• 589-18-4 4-Methylbenzyl alcohol 
• 17936-75-3 2,2,2-trichloro-1-(2,5-dimethyl-phenyl)-ethanol 
• 161236-76-6 (4,4-Dimethyl-4,5-dihydro-oxazol-2-yl)-(2,5-dimethyl-phenyl)-methanol 
• 128042-16-0 1-ethoxycarbonylamino-1-(2,5-dimethylphenyl)-2,2-dichloroethane 
• 128042-11-5 [2,2,2-Trichloro-1-(2,5-dimethyl-phenyl)-ethyl]-carbamic acid methyl ester 
• 128042-15-9 1-methoxycarbonylamino-1-(2,5-dimethylphenyl)-2,2-dichloroethane 
• 20809-75-0 Methyl-2-(2,5-dimethyl-phenyl)-2-hydroxy-3-oxo-succinat 

Downstream Products

• 5779-94-2 2,5-dimethylbenzaldehyde 

Relevant academic research and scientific papers

Benzodifurantrione compounds and process

Benzodifurantriones of Formula (1): STR1 in which W is unsubstituted or substituted aryl, a process for their preparation via dioxo intermediates and processes for their conversion into benzodifuranone dyes and compounds of Formula (7): STR2 are provided wherein R3 is --H, --COR2, --SO2 R2 -- which R2 is alkyl, cycloalkyl, aryl or aralkyl and R4 is --COOR2, --CONRR1 in which R and R1 each independently is --H, alkyl, cycloalkyl, aryl or aralkyl; --COOH or the alkali metal, alkaline earth metal or ammonium salts thereof; or --COX2 -- which X2 is halo.

Rearrangement of 2-(Arylmethoxy)methyl-2-oxazolines via Lithium Azaenolates: a Facile Synthetic Route to ortho-Methylmandelic Acid Derivatives

2-(Arylmethoxy)methyl-2-oxazolines, on treatment with LDA in THF at low temperature, rearrange to afford products which are hydrolysed to ortho-methylmandelic acids or α-(1-methyl-2-naphthyl)glycolic acid.

SYNTHESIS AND SOME PROPERTIES OF 1,1-DI(ALKOXYCARBONYLAMINO)-2,2-DIHALOGENO- AND 1,1-DI(ALKOXYCARBONYLAMINO)-2,2,2-TRIHALOGENOETHANES

1,1-Di(alkoxycarbonylamino)-2,2,2-trihalogenoethanes were obtained by heating trihalogenoacetaldehydes or their hydrates with urethanes in a ratio of 1:2 in the presence of catalytic amounts of concentrated sulfuric acid.The products were reduced selectively with aluminum amalgam in 90percent alcohol to 1,1-di(alkoxycarbonylamino)-2,2-dihalogenoethanes.Compounds of both types react smoothly with benzene and its homologs in the presence of concentrated sulfuric acid and give 1-alkoxycarbonylamino-1-aryl-2,2-dihalogeno- and 1-alkoxycarbonylamino-1-aryl-2,2,2-trihalogenoethanes respectively.In an alkaline medium the latter are cleaved to aryloxyacetic acid, and with phosphorus pentachloride they form 1-aryl-2,2-dihalogeno- and 1-aryl-2,2,2-trihalogenoethyl isocyanates.