6-aminohexanoic acid {4-[4-(6-aminohexanoylamino)benzyl]phenyl}amide

Base Information

• Chemical Name: 6-aminohexanoic acid {4-[4-(6-aminohexanoylamino)benzyl]phenyl}amide
• CAS No.: 132010-76-5
• Molecular Formula: C₂₅H₃₆N₄O₂
• Molecular Weight: 424.586
• Mol file: 132010-76-5.mol

Synonyms:6-aminohexanoic acid {4-[4-(6-aminohexanoylamino)benzyl]phenyl}amide

Chemical Property of 6-aminohexanoic acid {4-[4-(6-aminohexanoylamino)benzyl]phenyl}amide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 6-aminohexanoic acid {4-[4-(6-aminohexanoylamino)benzyl]phenyl}amide

There total 5 articles about 6-aminohexanoic acid {4-[4-(6-aminohexanoylamino)benzyl]phenyl}amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(5-{4-[4-(6-benzyloxycarbonylaminohexanoylamino)benzyl]phenylcarbamoyl}pentyl)carbamic acid benzyl ester (797805-12-0) → 6-aminohexanoic acid {4-[4-(6-aminohexanoylamino)benzyl]phenyl}amide (132010-76-5)

Guidance literature:

With hydrogen bromide; acetic acid; at 20 ℃; for 4h;

DOI:10.1021/jm0494366

Reference yield: 85.0%

caprolactam (105-60-2,9012-16-2) + 4,4'-diamino diphenyl methane (101-77-9) → 6-aminohexanoic acid {4-[4-(6-aminohexanoylamino)benzyl]phenyl}amide (132010-76-5)

Guidance literature:

With alkali hypophosphate; In 1-methyl-pyrrolidin-2-one; for 24h;

DOI:10.1039/c4ra14383c

Reference yield: 85.0%

4,4'-diamino diphenyl methane (101-77-9) + 6-aminohexanoic acid (60-32-2,93208-38-9) → 6-aminohexanoic acid {4-[4-(6-aminohexanoylamino)benzyl]phenyl}amide (132010-76-5)

Guidance literature:

With 1-methyl-pyrrolidin-2-one; at 100 ℃; for 24h;

DOI:10.1039/c4ra06211f

upstream raw materials:

(5-{4-[4-(6-benzyloxycarbonylaminohexanoylamino)benzyl]phenylcarbamoyl}pentyl)carbamic acid benzyl ester

6-(benzyloxycarbonylamino)hexanoic acid

4,4'-diamino diphenyl methane

6-aminohexanoic acid

Downstream raw materials:

6-[ethyl-(2-methoxy-benzyl)-amino]-hexanoic acid [4-(4-{6-[ethyl-(2-methoxy-benzyl)-amino]-hexanoylamino}-benzyl)-phenyl]-amide

6-(2-methoxybenzylamino)hexanoic acid (4-{4-[6-(2-methoxybenzylamino)hexanoylamino]benzyl}phenyl)amide