2-benzyl-1,1,4-trioxo-1,2,3,4-tetrahydro-1λ⁶-benzo[e][1,2]thiazine-3-carboxylic acid anilide

Base Information

• Chemical Name: 2-benzyl-1,1,4-trioxo-1,2,3,4-tetrahydro-1λ⁶-benzo[e][1,2]thiazine-3-carboxylic acid anilide
• CAS No.: 35510-99-7
• Molecular Formula: C₂₂H₁₈N₂O₄S
• Molecular Weight: 406.462
• Mol file: 35510-99-7.mol

Synonyms:2-benzyl-1,1,4-trioxo-1,2,3,4-tetrahydro-1λ⁶-benzo[e][1,2]thiazine-3-carboxylic acid anilide

Chemical Property of 2-benzyl-1,1,4-trioxo-1,2,3,4-tetrahydro-1λ⁶-benzo[e][1,2]thiazine-3-carboxylic acid anilide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-benzyl-1,1,4-trioxo-1,2,3,4-tetrahydro-1λ⁶-benzo[e][1,2]thiazine-3-carboxylic acid anilide

There total 4 articles about 2-benzyl-1,1,4-trioxo-1,2,3,4-tetrahydro-1λ⁶-benzo[e][1,2]thiazine-3-carboxylic acid anilide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-benzyl-2,3-dihydro-spiro[benzo[e][1,2]thiazine-4,2'-[1,3]dioxolane] 1,1-dioxide (35624-81-8) → 2-benzyl-1,1,4-trioxo-1,2,3,4-tetrahydro-1λ6-benzo[e][1,2]thiazine-3-carboxylic acid anilide (35510-99-7)

Guidance literature:

Multi-step reaction with 2 steps

1: (hydrolysis)

2: (i) NaH, DMF, (ii) /BRN= 471391/

DOI:10.1021/jm00294a008

Reference yield:

2,3-dihydro-spiro[benzo[e][1,2]thiazine-4,2'-[1,3]dioxolane] 1,1-dioxide (5510-31-6) → 2-benzyl-1,1,4-trioxo-1,2,3,4-tetrahydro-1λ6-benzo[e][1,2]thiazine-3-carboxylic acid anilide (35510-99-7)

Guidance literature:

Multi-step reaction with 3 steps

2: (hydrolysis)

3: (i) NaH, DMF, (ii) /BRN= 471391/

DOI:10.1021/jm00294a008

Reference yield:

benzyl bromide (100-39-0) → 2-benzyl-1,1,4-trioxo-1,2,3,4-tetrahydro-1λ6-benzo[e][1,2]thiazine-3-carboxylic acid anilide (35510-99-7)

Guidance literature:

Multi-step reaction with 3 steps

2: (hydrolysis)

3: (i) NaH, DMF, (ii) /BRN= 471391/

DOI:10.1021/jm00294a008

upstream raw materials:

2-benzyl-1,1-dioxo-2,3-dihydro-1H-1λ⁶-benzo[e][1,2]thiazin-4-one

phenyl isocyanate

2-benzyl-2,3-dihydro-spiro[benzo[e][1,2]thiazine-4,2'-[1,3]dioxolane] 1,1-dioxide

2,3-dihydro-spiro[benzo[e][1,2]thiazine-4,2'-[1,3]dioxolane] 1,1-dioxide

Downstream raw materials:

1,1,4-trioxo-1,2,3,4-tetrahydro-1λ⁶-benzo[e][1,2]thiazine-3-carboxylic acid anilide