methyl cis, cis-2,3-diphenylcyclopropanecarboxylate

Base Information

• Chemical Name: methyl cis, cis-2,3-diphenylcyclopropanecarboxylate
• CAS No.: 7381-89-7
• Molecular Formula: C₁₈H₁₈O₂
• Molecular Weight: 266.34
• Mol file: 7381-89-7.mol

Synonyms:methyl cis, cis-2,3-diphenylcyclopropanecarboxylate

Chemical Property of methyl cis, cis-2,3-diphenylcyclopropanecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of methyl cis, cis-2,3-diphenylcyclopropanecarboxylate

There total 14 articles about methyl cis, cis-2,3-diphenylcyclopropanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

diazoacetic acid ethyl ester (623-73-4) + (E)-1,2-diphenyl-ethene (103-30-0) → ethyl ester of (racemic) 2,3-diphenylcyclopropane-1-carboxylic acid (7381-89-7,64200-25-5,64551-34-4,95119-41-8)

Guidance literature:

With [Cr(bathophenanthroline)₃](BF₄)₃; In dichloromethane; 1,2-dichloro-ethane; for 14h; Reagent/catalyst; Solvent; Concentration; Catalytic behavior; Irradiation; Sealed tube;

DOI:10.1021/acs.orglett.7b01095

Reference yield: 83.0%

diazoacetic acid ethyl ester (623-73-4) + stilbene (588-59-0) → ethyl ester of (racemic) 2,3-diphenylcyclopropane-1-carboxylic acid (7381-89-7,64200-25-5,64551-34-4,95119-41-8)

Guidance literature:

With tris(1,10-phenanthroline)iron(III) tris(hexafluorophosphate); In 1,2-dichloro-ethane; at 0 ℃; for 27h;

Reference yield: 81.0%

diazoacetic acid ethyl ester (623-73-4) + cis-stilben (645-49-8) → ethyl ester of (racemic) 2,3-diphenylcyclopropane-1-carboxylic acid (7381-89-7,64200-25-5,64551-34-4,95119-41-8)

Guidance literature:

tris(2,4-dibromophenyl)aminium hexachloroantimonate; at -78 ℃;

DOI:10.1021/ja00274a070

upstream raw materials:

diazoacetic acid ethyl ester

cis-stilben

ethyl ester of 2β,3β-diphenylcyclopropane-1α-carboxylic acid

(E)-1,2-diphenyl-ethene

Downstream raw materials:

cis, cis-1-hydroxymethyl-2,3-diphenylcyclopropane

cis-2,3-diphenylcyclopropanecarboxylic acid

ethyl 2-benzyl-3-phenylpropionate

ethyl 3,4-diphenylbutanoate

Refernces

• 1、 Cho, Yong Hyun,Kim, Jae Hyung,An, Hyeju,Ahn, Kwang-Hyun,Kang, Eun Joo. "Cycloaddition Reactions of Alkene Radical Cations using Iron(III)-Phenanthroline Complex". supporting information. p. 2183 - 2188. Retrieved 2020/04/29.
• 2、 Chen, Chen,Feng, Shiyu,Chan, Kin Shing. "Rhodium Porphyrin Catalyzed Regioselective Transfer Hydrogenolysis of C-C σ-Bonds in Cyclopropanes with iPrOH". supporting information. p. 2582 - 2589. Retrieved 2019/07/02.