4-Chloro-2-phenylbenzoic acid

Base Information

Chemical Name:4-Chloro-2-phenylbenzoic acid
CAS No.:107274-51-1
Molecular Formula:C₁₃H₉ClO₂
Molecular Weight:232.666
Hs Code.:
DSSTox Substance ID:DTXSID90465467
Wikidata:Q82291430

Synonyms:4-CHLORO-2-PHENYLBENZOIC ACID;107274-51-1;SCHEMBL7554300;DTXSID90465467;MFCD14701683;EN300-7439946;Z1947366264

Suppliers and Price of 4-Chloro-2-phenylbenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alichem
5-Chlorobiphenyl-2-carboxylicacid
500mg
$ 798.70

AK Scientific
4-Chloro-2-phenylbenzoicacid
5g
$ 1772.00

AK Scientific
4-Chloro-2-phenylbenzoicacid
500mg
$ 532.00

AK Scientific
4-Chloro-2-phenylbenzoicacid
100mg
$ 262.00

Total 2 raw suppliers

Chemical Property of 4-Chloro-2-phenylbenzoic acid

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:232.0291072
Heavy Atom Count:16
Complexity:248

Purity/Quality:

97% ^*data from raw suppliers

5-Chlorobiphenyl-2-carboxylicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=C(C=CC(=C2)Cl)C(=O)O

Technology Process of 4-Chloro-2-phenylbenzoic acid

There total 10 articles about 4-Chloro-2-phenylbenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 133721-82-1
methyl 5-chloro-[1,1'-biphenyl]-2-carboxylate

: 107274-51-1
5-chloro-[1,1'-biphenyl]-2-carboxylic acid

Guidance literature:: With lithium hydroxide monohydrate; In methanol; water; Reflux;

Reference yield:

: 22717-55-1
methyl 4-chloro-2-hydroxybenzoate

: 107274-51-1
5-chloro-[1,1'-biphenyl]-2-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / -78 - 20 °C

2: potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / N,N-dimethyl-formamide / 110 °C

3: lithium hydroxide monohydrate / water; methanol / Reflux

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; lithium hydroxide monohydrate; potassium carbonate; triethylamine; In methanol; dichloromethane; water; N,N-dimethyl-formamide;

Reference yield:

: 212892-02-9
methyl 4-chloro-2-(((trifluoromethyl)sulfonyl)oxy)benzoate

: 107274-51-1
5-chloro-[1,1'-biphenyl]-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / N,N-dimethyl-formamide / 110 °C

2: lithium hydroxide monohydrate / water; methanol / Reflux

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; lithium hydroxide monohydrate; potassium carbonate; In methanol; water; N,N-dimethyl-formamide;