2-{[5-(4-chlorophenyl)-4-iodo-1-phenyl-1H-pyrazol-3-yl]methyl}-N-cyclopropylacrylamide

Base Information

Chemical Name:2-{[5-(4-chlorophenyl)-4-iodo-1-phenyl-1H-pyrazol-3-yl]methyl}-N-cyclopropylacrylamide
CAS No.:1214996-77-6
Molecular Formula:C₂₂H₁₉ClIN₃O
Molecular Weight:503.77
Hs Code.:

Synonyms:2-{[5-(4-chlorophenyl)-4-iodo-1-phenyl-1H-pyrazol-3-yl]methyl}-N-cyclopropylacrylamide

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Chemical Property of 2-{[5-(4-chlorophenyl)-4-iodo-1-phenyl-1H-pyrazol-3-yl]methyl}-N-cyclopropylacrylamide

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Technology Process of 2-{[5-(4-chlorophenyl)-4-iodo-1-phenyl-1H-pyrazol-3-yl]methyl}-N-cyclopropylacrylamide

There total 1 articles about 2-{[5-(4-chlorophenyl)-4-iodo-1-phenyl-1H-pyrazol-3-yl]methyl}-N-cyclopropylacrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 1214996-60-7
2-{[5-(4-chlorophenyl)-4-iodo-1-phenyl-1H-pyrazol-3-yl]methyl}acrylic acid

: 765-30-0
Cyclopropylamine

: 1214996-77-6
2-{[5-(4-chlorophenyl)-4-iodo-1-phenyl-1H-pyrazol-3-yl]methyl}-N-cyclopropylacrylamide

Guidance literature:: 2-{[5-(4-chlorophenyl)-4-iodo-1-phenyl-1H-pyrazol-3-yl]methyl}acrylic acid; With benzotriazol-1-ol; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

Cyclopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 2h;
DOI:10.1002/adsc.200900438

Reference yield: 50.0%

: 1214996-77-6
2-{[5-(4-chlorophenyl)-4-iodo-1-phenyl-1H-pyrazol-3-yl]methyl}-N-cyclopropylacrylamide

: 1214997-13-3
(E)-3-[5-(4-chlorophenyl)-1-phenyl-1H-pyrazol-3-yl]-N-cyclopropyl-2-methylprop-2-enamide

: 1214996-95-8
3-(4-chlorophenyl)-4-cyclopropyl-6-methyl-2-phenyl-2,4-dihydro-5H-pyrazolo[4,3-b]pyridin-5-one

Guidance literature:: With copper(l) iodide; caesium carbonate; ethylenediamine; In N,N-dimethyl-formamide; at 100 ℃; for 24h; Inert atmosphere;
DOI:10.1002/adsc.200900438