Technology Process of 4-isopropyl-2,3,5-trimethoxybenzyl chloride
There total 8 articles about 4-isopropyl-2,3,5-trimethoxybenzyl chloride which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrachloromethane; triphenylphosphine;
In
acetonitrile;
at 20 ℃;
for 3h;
DOI:10.1021/jo051082i
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 11.4 g / hydrogen / palladium on charcoal / ethanol / 36 h
2.1: n-butyllithium / tetrahydrofuran; hexane / 5 h / -78 - 0 °C
2.2: 75 percent / tetrahydrofuran; hexane / -78 - 0 °C
3.1: 94 percent / sodium borohydride / methanol / 0.5 h / -20 °C
4.1: 79 percent / carbon tetrachloride; triphenylphosphine / acetonitrile / 3 h / 20 °C
With
tetrachloromethane; sodium tetrahydroborate; n-butyllithium; hydrogen; triphenylphosphine;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; ethanol; hexane; acetonitrile;
DOI:10.1021/jo051082i
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: n-butyllithium / diethyl ether; hexane / 3.5 h / 0 - 20 °C
1.2: 75 percent / diethyl ether; hexane / -60 - 20 °C
2.1: 94 percent / lithium hydroxide monohydrate / tetrahydrofuran / 6 h / Heating
3.1: magnesium / diethyl ether / 3 h / Heating
3.2: diethyl ether / 1 h / Heating
4.1: acetic acid / 3 h / Heating
5.1: 11.4 g / hydrogen / palladium on charcoal / ethanol / 36 h
6.1: n-butyllithium / tetrahydrofuran; hexane / 5 h / -78 - 0 °C
6.2: 75 percent / tetrahydrofuran; hexane / -78 - 0 °C
7.1: 94 percent / sodium borohydride / methanol / 0.5 h / -20 °C
8.1: 79 percent / carbon tetrachloride; triphenylphosphine / acetonitrile / 3 h / 20 °C
With
tetrachloromethane; lithium hydroxide; sodium tetrahydroborate; n-butyllithium; hydrogen; magnesium; acetic acid; triphenylphosphine;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; diethyl ether; ethanol; hexane; acetonitrile;
DOI:10.1021/jo051082i
