156723-06-7

Basic information

• Product Name: 4-(1-methylethyl)-2,3,5-trimethoxyphenylmethyl alcohol
• Synonyms: 4-(1-methylethyl)-2,3,5-trimethoxyphenylmethyl alcohol
• CAS NO: 156723-06-7
• Molecular Weight: 240.299
• Mol File: 156723-06-7.mol

Chemical Properties

• CAS DataBase Reference: 4-(1-methylethyl)-2,3,5-trimethoxyphenylmethyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1-methylethyl)-2,3,5-trimethoxyphenylmethyl alcohol(156723-06-7)
• EPA Substance Registry System: 4-(1-methylethyl)-2,3,5-trimethoxyphenylmethyl alcohol(156723-06-7)

Safety Data

• Hazardous Substances Data: 156723-06-7(Hazardous Substances Data)

Upstream product

• 156723-05-6 methyl 4-(1-methylethyl)-2,3,5-trimethoxybenzoate 
• 866464-91-7 4-(1-methylethyl)-2,3,5-trimethoxybenzaldehyde 
• 914618-38-5 6-(hydroxymethyl)-3-isopropyl-2,4-dimethoxyphenol 
• 74-88-4 methyl iodide 
• 36873-96-8 2,3,5-trimethoxybenzoic acid 
• 1167996-79-3 C₁₃H₁₆Br₂O₃ 
• 124-41-4 sodium methylate 
• 23030-39-9 1-bromo-2,3,5-trimethoxybenzene 
• 60241-76-1 3-(1-methyl-1-hydroxyethyl)-1,2,4-trimethoxybenzene 
• 60241-74-9 2,3,6-trimethoxybenzoic acid 
• 60241-75-0 methyl 2,3,6-trimethoxybenzoate 
• 60241-77-2 1,2,4-trimethoxy-3-(prop-1-en-2-yl)benzene 
• 60241-78-3 3-(1-methylethyl)-1,2,4-trimethoxybenzene 
• 135-77-3 1,2,4-trimethoxy-benzene 

Downstream Products

• 156723-07-8 2-(1-methylethyl)-1,3,4-trimethoxy-5-(bromomethyl)benzene 
• 866464-96-2 4-isopropyl-2,3,5-trimethoxybenzyl chloride 
• 914618-43-2 1-({[tert-butyl(dimethyl)silyl]oxy}methyl)-4-isopropyl-2,3,5-trimethoxybenzene 
• 914618-39-6 1-(iodomethyl)-4-isopropyl-2,3,5-trimethoxybenzene 
• 135626-42-5 2-isopropyl-1,3,4-trimethoxy-5-methylbenzene 
• 1352034-35-5 C₃₃H₄₁F₃O₆ 
• 1352034-36-6 C₃₃H₄₁F₃O₆ 
• 1217296-80-4 4-isopropyl-2,3,5-trimethoxydihydrocinnamic acid 
• 1217296-89-3 ethyl (4-isopropyl-2,3,5-trimethoxy)dihydrocinnamate 
• 1441209-67-1 (S)-N-((8-isopropyl-6,7,9-trimethoxy-1-methyl-2,3,4,5-tetrahydro-1H-dibenzo[a,d][7]annulen-1-yl)methyl)-4-bromobenzamide 
• 156723-09-0 3-methoxy-6,6-dimethyl-2-[4-(1-methylethyl)-2,3,5-trimethoxyphenylmethyl]-2-cyclohexenone 
• 156723-08-9 4,4-dimethyl-2-[4-(1-methylethyl)-2,3,5-trimethoxyphenyl-methyl]-1,3-cyclohexanedione 
• 156723-10-3 3-ethenyl-4,4-dimethyl-2-[4-(1-methylethyl)-2,3,5-trimethoxyphenylmethyl]-2-cyclohexenone 

Relevant articles and documents

Synthesis of (±)- and (+)-perovskone

A biomimetic synthesis of the triterpene (±)-perovskone was achieved featuring a remarkable polycyclization process in which three rings, four bonds, and five stereocenters were created in a single operation in 82% yield. This convergent synthesis required 16 steps, starting from vanillin, and proceeded in 9% overall yield. A second route to prepare optically active quinone 2 took 15 steps in 36% overall yield and featured a palladium-catalyzed reductive allylic transposition to establish the C-5 chirality stereospecifically. Quinone (-)-2 was converted to (+)-perovskone (1) via a polycyclization cascade, which created four rings, five bonds, and six stereocenters in a single operation in 50% yield.

Ga(IIl)-catalyzed cycloisomerization approach to (±)-icetexone and (±)-epi-icetexone

"Chemical eqation presented" A Ga(III)-catalyzed cycloisomerization reaction provides expedient access to a benzannulated cycloheptadiene bearing a cyano group, which has been applied to the syntheses of several icetexane diterpenoids including icetexone

Total synthesis of (+)-19-deoxyicetexone, (-)-Lcetexone, and (+)-5-epi-icetexone

The first asymmetric total syntheses of 19-deoxylcetexone, Icetexone, and 5-epl-Icetexone was achieved from eplmerlc tricyclic dlenes.

Total synthesis of (±)-komaroviquinone

(±)-Komaroviquinone (1) was synthesized from 3,4,5-trimethoxybenzoic acid in twenty-two steps. The key transformations in this synthesis are: (1) the construction of the cycloheptane ring via a Friedel-Crafts cyclialkylation; (2) a regiospecific benzylic oxidation; (3) a conformationally controlled introduction of the C(10) hydroxyl group and (4) intramolecular hemi-acetal formation.

A formal total synthesis of salvadione

The tricyclic 6-7-6 core structure of the triterpene salvadione (1) was obtained in an efficient manner from the aryl bromide 16 and the alkyl iodide 35 carrying a methylenecyclohexane group at the terminus. Alkylation of the anion derived from 16 with th

Stereoselective syntheses of (±)-komaroviquinone and (±)-faveline methyl ether through intramolecular Heck reaction

An efficient, flexible, and stereoselective convergent route for constructing the trans-10-hydroxy-1,1-dimethyloctahydrodibenzo[a,d]cyclohepten- 7-ones (5a-c) was achieved via intramolecular Heck reaction. This strategy has been successfully implemented for the syntheses of (±)-komaroviquinone (3) through (±)-coulterone dimethyl ether (5c) and (±)-faveline methyl ether (1a).