1-benzyl-5,6-diamino-3-methyl uracil

Base Information

• Chemical Name: 1-benzyl-5,6-diamino-3-methyl uracil
• CAS No.: 132560-34-0
• Molecular Formula: C₁₂H₁₄N₄O₂
• Molecular Weight: 246.269
• Mol file: 132560-34-0.mol

Synonyms:1-benzyl-5,6-diamino-3-methyl uracil

Chemical Property of 1-benzyl-5,6-diamino-3-methyl uracil

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-benzyl-5,6-diamino-3-methyl uracil

There total 3 articles about 1-benzyl-5,6-diamino-3-methyl uracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

6-amino-1-benzyl-3-methyl-5-nitroso uracil (132588-35-3) → 1-benzyl-5,6-diamino-3-methyl uracil (132560-34-0)

Guidance literature:

With sodium dithionite; In water; at 70 - 80 ℃; for 1h;

Reference yield:

N-methyl-N'-benzylurea (6957-05-7) → 1-benzyl-5,6-diamino-3-methyl uracil (132560-34-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) acetic anhydride, 2.) 10percent aq. NaOH / 1.) 70 deg C, 2 h, 2.) from 20 to 70 deg C, 1 h

2: NaNO₂, AcOH / H₂O / 2 h / Ambient temperature

3: Na₂S₂O₄, 25percent aq. NH₄OH / 20 - 50 °C

With ammonium hydroxide; sodium hydroxide; sodium dithionite; acetic anhydride; acetic acid; sodium nitrite; In water;

DOI:10.1016/0223-5234(90)90130-U

Reference yield:

6-amino-1-benzyl-3-methyl uracil (53681-51-9) → 1-benzyl-5,6-diamino-3-methyl uracil (132560-34-0)

Guidance literature:

Multi-step reaction with 2 steps

1: NaNO₂, AcOH / H₂O / 2 h / Ambient temperature

2: Na₂S₂O₄, 25percent aq. NH₄OH / 20 - 50 °C

With ammonium hydroxide; sodium dithionite; acetic acid; sodium nitrite; In water;

DOI:10.1016/0223-5234(90)90130-U

upstream raw materials:

6-amino-1-benzyl-3-methyl-5-nitroso uracil

N-methyl-N'-benzylurea

6-amino-1-benzyl-3-methyl uracil

Downstream raw materials:

1-methyl-3-benzyl-8-(but-3-ynyl)-xanthine