4-(3-(cyclohexylmethyl)-1H-indol-2-yl)-N,N-dimethyl-1-phenylcyclohexanamine

Base Information

• Chemical Name: 4-(3-(cyclohexylmethyl)-1H-indol-2-yl)-N,N-dimethyl-1-phenylcyclohexanamine
• CAS No.: 1004543-74-1
• Molecular Formula: C₂₉H₃₈N₂
• Molecular Weight: 414.634
• Mol file: 1004543-74-1.mol

Synonyms:4-(3-(cyclohexylmethyl)-1H-indol-2-yl)-N,N-dimethyl-1-phenylcyclohexanamine

Chemical Property of 4-(3-(cyclohexylmethyl)-1H-indol-2-yl)-N,N-dimethyl-1-phenylcyclohexanamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 4-(3-(cyclohexylmethyl)-1H-indol-2-yl)-N,N-dimethyl-1-phenylcyclohexanamine

There total 3 articles about 4-(3-(cyclohexylmethyl)-1H-indol-2-yl)-N,N-dimethyl-1-phenylcyclohexanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(+/-)-2-(4-(dimethylamino)-4-phenylcyclohex-1-enyl)-3-(cyclohexylmethyl)-1H-indole hydrochloride → 4-(3-(cyclohexylmethyl)-1H-indol-2-yl)-N,N-dimethyl-1-phenylcyclohexanamine (1004543-76-3) + 4-(3-(cyclohexylmethyl)-1H-indol-2-yl)-N,N-dimethyl-1-phenylcyclohexanamine (1004543-74-1)

Guidance literature:

(+/-)-2-(4-(dimethylamino)-4-phenylcyclohex-1-enyl)-3-(cyclohexylmethyl)-1H-indole hydrochloride; With tin; hydrogen bromide; In acetic acid; at 5 - 20 ℃;

With sodium hydroxide;

Reference yield:

3-(cyclohexylmethyl)-1H-indole (101104-31-8) → 4-(3-(cyclohexylmethyl)-1H-indol-2-yl)-N,N-dimethyl-1-phenylcyclohexanamine (1004543-74-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: trifluorormethanesulfonic acid / dichloromethane / 90 h / 20 °C

1.2: 0.17 h

1.3: 3 h / 20 °C

2.1: tin; hydrogen bromide / acetic acid / 5 - 20 °C

With tin; trifluorormethanesulfonic acid; hydrogen bromide; In dichloromethane; acetic acid;

Reference yield:

4-dimethylamino-4-phenylcyclohexanone (65619-20-7) → 4-(3-(cyclohexylmethyl)-1H-indol-2-yl)-N,N-dimethyl-1-phenylcyclohexanamine (1004543-74-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: trifluorormethanesulfonic acid / dichloromethane / 90 h / 20 °C

1.2: 0.17 h

1.3: 3 h / 20 °C

2.1: tin; hydrogen bromide / acetic acid / 5 - 20 °C

With tin; trifluorormethanesulfonic acid; hydrogen bromide; In dichloromethane; acetic acid;

upstream raw materials:

3-(cyclohexylmethyl)-1H-indole

4-dimethylamino-4-phenylcyclohexanone