Technology Process of C33H39NO4Si
There total 6 articles about C33H39NO4Si which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C32H37NO4Si;
With
sodium hexamethyldisilazane;
In
tetrahydrofuran;
at -78 ℃;
for 1h;
methyl iodide;
In
tetrahydrofuran;
at -78 ℃;
for 24h;
diastereoselective reaction;
DOI:10.1021/jm400542h
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sodium hexamethyldisilazane / tetrahydrofuran / 0.5 h / 0 °C
1.2: 0.33 h / 0 °C
2.1: water; hydrogenchloride / tetrahydrofuran / 1 h / 0 °C
3.1: 2-methyl-but-2-ene; sodium dihydrogenphosphate dihydrate; sodium chlorite / tert-butyl alcohol; water / 0.67 h / 20 °C
4.1: triethylamine / dichloromethane / 1 h / 0 °C
5.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C
5.2: 1 h / -78 °C
6.1: sodium hexamethyldisilazane / tetrahydrofuran / 1 h / -78 °C
6.2: 24 h / -78 °C
With
hydrogenchloride; sodium chlorite; n-butyllithium; sodium dihydrogenphosphate dihydrate; 2-methyl-but-2-ene; water; sodium hexamethyldisilazane; triethylamine;
In
tetrahydrofuran; hexane; dichloromethane; water; tert-butyl alcohol;
1.1: |Wittig Olefination;
DOI:10.1021/jm400542h
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: triethylamine / dichloromethane / 1 h / 0 °C
2.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C
2.2: 1 h / -78 °C
3.1: sodium hexamethyldisilazane / tetrahydrofuran / 1 h / -78 °C
3.2: 24 h / -78 °C
With
n-butyllithium; sodium hexamethyldisilazane; triethylamine;
In
tetrahydrofuran; hexane; dichloromethane;
DOI:10.1021/jm400542h
