ethyl 3-((4-hydroxyphenyl)(2-methoxybenzyl)amino)-3-oxopropanoate

Base Information

• Chemical Name: ethyl 3-((4-hydroxyphenyl)(2-methoxybenzyl)amino)-3-oxopropanoate
• CAS No.: 1169411-29-3
• Molecular Formula: C₁₉H₂₁NO₅
• Molecular Weight: 343.379
• Mol file: 1169411-29-3.mol

Synonyms:ethyl 3-((4-hydroxyphenyl)(2-methoxybenzyl)amino)-3-oxopropanoate

Chemical Property of ethyl 3-((4-hydroxyphenyl)(2-methoxybenzyl)amino)-3-oxopropanoate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of ethyl 3-((4-hydroxyphenyl)(2-methoxybenzyl)amino)-3-oxopropanoate

There total 1 articles about ethyl 3-((4-hydroxyphenyl)(2-methoxybenzyl)amino)-3-oxopropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

C14H15NO2 (665014-68-6) + ethyl chlorocarbonylacetate (36239-09-5) → ethyl 3-((4-hydroxyphenyl)(2-methoxybenzyl)amino)-3-oxopropanoate (1169411-29-3)

Guidance literature:

With pyridine; In dichloromethane; at 0 - 20 ℃;

DOI:10.1021/ol901005x

Reference yield: 84.0%

ethyl 3-((4-hydroxyphenyl)(2-methoxybenzyl)amino)-3-oxopropanoate (1169411-29-3) → ethyl 1-(2-methoxybenzyl)-2,7-dioxo-1-azaspiro[3.5]nona-5,8-diene-3-carboxylate (1169411-59-9)

Guidance literature:

ethyl 3-((4-hydroxyphenyl)(2-methoxybenzyl)amino)-3-oxopropanoate; With dmap; copper(ll) sulfate pentahydrate; In methanol; at 0 ℃; for 0.166667h;

With [bis(acetoxy)iodo]benzene; In methanol; at 0 ℃;

DOI:10.1021/ol901005x

upstream raw materials:

C₁₄H₁₅NO₂

ethyl chlorocarbonylacetate

Downstream raw materials:

ethyl 1-(2-methoxybenzyl)-2,7-dioxo-1-azaspiro[3.5]nona-5,8-diene-3-carboxylate