C₁₈H₁₂N₄O

Base Information

• Chemical Name: C₁₈H₁₂N₄O
• CAS No.: 1194043-02-1
• Molecular Formula: C₁₈H₁₂N₄O
• Molecular Weight: 300.319
• Mol file: 1194043-02-1.mol

Synonyms:C₁₈H₁₂N₄O

Chemical Property of C₁₈H₁₂N₄O

Chemical Property:

Purity/Quality:

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• Pictogram(s):  
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MSDS Files:

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Technology Process of C₁₈H₁₂N₄O

There total 1 articles about C₁₈H₁₂N₄O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

5-[(7-bromo-3-methyl-1H-indazol-4-yl)oxy]isophthalonitrile (1123741-64-9) + tri-n-butyl(vinyl)tin (7486-35-3) → C18H12N4O (1194043-02-1)

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tris-(o-tolyl)phosphine; In 1,4-dioxane; for 24h; Reflux; Inert atmosphere;

DOI:10.1021/jm801322h

Reference yield:

C18H12N4O (1194043-02-1) → C17H10N4O2 (1194043-71-4)

Guidance literature:

C₁₈H₁₂N₄O; With osmium(VIII) oxide; 4-methylmorpholine N-oxide; In tetrahydrofuran; water; tert-butyl alcohol; at 20 ℃; for 15h;

With sodium periodate; sodium hydrogencarbonate; In tetrahydrofuran; water; tert-butyl alcohol; at 20 ℃; for 1h;

DOI:10.1021/jm801322h

upstream raw materials:

5-[(7-bromo-3-methyl-1H-indazol-4-yl)oxy]isophthalonitrile

tri-n-butyl(vinyl)tin

Downstream raw materials:

C₁₇H₁₀N₄O₂