5-Bromo-1-benzothiophene-2-carboxylic acid

Base Information

Chemical Name:5-Bromo-1-benzothiophene-2-carboxylic acid
CAS No.:7312-10-9
Molecular Formula:C9H5BrO2S
Molecular Weight:257.107
Hs Code.:2934999090
European Community (EC) Number:692-275-4
DSSTox Substance ID:DTXSID20353282
Wikidata:Q82130767
Mol file:7312-10-9.mol

Synonyms:5-bromo-1-benzothiophene-2-carboxylic acid;7312-10-9;5-bromobenzo[b]thiophene-2-carboxylic acid;5-Bromo-benzo[b]thiophene-2-carboxylic acid;Benzo[b]thiophene-2-carboxylic acid, 5-bromo-;MFCD01929338;5-bromobenzothiophene-2-carboxylic acid;Benzo[b]thiophene-2-carboxylicacid, 5-bromo-;AN-278/13643032;SCHEMBL700588;DTXSID20353282;ONNFNEFYXIPHCA-UHFFFAOYSA-N;AMY33892;FD7313;STL474501;AKOS005070291;BP-13232;SY104077;CS-0033871;FT-0680322;EN300-186714;3T-1185;5-BROMO-1-benzo[b]thiophene-2-CARBOXYLIC ACID;5-BROMO-1-BENZOTHIOPHENE-2-CARBOXYLICACID;J-516786;5-bromo-1-benzothiophene-2-carboxylic acid, AldrichCPR;Z1269202680

Suppliers and Price of 5-Bromo-1-benzothiophene-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Bromo-1-benzothiophene-2-carboxylicAcid
50mg
$ 60.00

SynQuest Laboratories
5-Bromobenzo[b]thiophene-2-carboxylic acid
1 g
$ 50.00

Matrix Scientific
5-Bromo-1-benzothiophene-2-carboxylic acid >95%
5g
$ 587.00

Matrix Scientific
5-Bromo-1-benzothiophene-2-carboxylic acid >95%
1g
$ 163.00

Matrix Scientific
5-Bromo-1-benzothiophene-2-carboxylic acid >95%
500mg
$ 106.00

J&W Pharmlab
5-Bromo-benzo[b]thiophene-2-carboxylicacid 95%
1g
$ 66.00

J&W Pharmlab
5-Bromo-benzo[b]thiophene-2-carboxylicacid 95%
5g
$ 280.00

Crysdot
5-Bromobenzo[b]thiophene-2-carboxylicacid 95+%
25g
$ 521.00

Chemenu
5-Bromo-1-benzothiophene-2-carboxylicacid 95%+
1g
$ 75.00

Chemenu
5-Bromo-1-benzothiophene-2-carboxylicacid 95%+
5g
$ 244.00

Total 29 raw suppliers

Chemical Property of 5-Bromo-1-benzothiophene-2-carboxylic acid

Chemical Property:

Vapor Pressure:3.8E-08mmHg at 25°C
Melting Point:230-234 °C
Refractive Index:1.738
Boiling Point:429.7 °C at 760 mmHg
PKA:3.29±0.30(Predicted)
Flash Point:213.7 °C
PSA：65.54000
Density:1.813 g/cm³
LogP:3.36200
Storage Temp.:2-8°C(protect from light)
XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:255.91936
Heavy Atom Count:13
Complexity:222

Purity/Quality:

99%, ^*data from raw suppliers

5-Bromo-1-benzothiophene-2-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,Xn
Statements: 22-36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=C1Br)C=C(S2)C(=O)O

Technology Process of 5-Bromo-1-benzothiophene-2-carboxylic acid

There total 6 articles about 5-Bromo-1-benzothiophene-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 7312-11-0
5-bromo-1-benzothiophene-2-carboxylic acid methyl ester

: 7312-10-9
5-bromo-1-benzothiophene-2-carboxylic acid

Guidance literature:: With potassium hydroxide; In water; for 3h; Reflux;
DOI:10.1016/j.ejmech.2019.04.024

Reference yield:

: 4923-87-9
5-bromobenzo[b]thiophene

: 124-38-9,18923-20-1
carbon dioxide

: 7312-10-9
5-bromo-1-benzothiophene-2-carboxylic acid

Guidance literature:: 5-bromobenzo[b]thiophene; With lithium diisopropyl amide; In tetrahydrofuran; at -60 - -30 ℃; for 1h; Inert atmosphere;

carbon dioxide; In tetrahydrofuran; at -60 - 0 ℃; for 1h;

With hydrogenchloride; In tetrahydrofuran; water;