(2E,4E)-3-Methyl-5-(2,6,6-triMethyl-1,3-cyclohexadien-1-yl)-2,4-pentadienenitrile

Base Information

Chemical Name:(2E,4E)-3-Methyl-5-(2,6,6-triMethyl-1,3-cyclohexadien-1-yl)-2,4-pentadienenitrile
CAS No.:20109-91-5
Molecular Formula:C₁₅H₁₉N
Molecular Weight:213.323
Hs Code.:
Mol file:20109-91-5.mol

Synonyms:(2E,4E)-3-methyl-5-(2,6,6-trimethyl-1,3-cyclohexadienyl)-2,4-pentanedienenitrile

Suppliers and Price of (2E,4E)-3-Methyl-5-(2,6,6-triMethyl-1,3-cyclohexadien-1-yl)-2,4-pentadienenitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2E,4E)-3-Methyl-5-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)-2,4-pentadienenitrile
2.5mg
$ 140.00

Medical Isotopes, Inc.
(2E,4E)-3-Methyl-5-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)-2,4-pentadienenitrile
10 mg
$ 900.00

Total 3 raw suppliers

Chemical Property of (2E,4E)-3-Methyl-5-(2,6,6-triMethyl-1,3-cyclohexadien-1-yl)-2,4-pentadienenitrile

Chemical Property:

Storage Temp.:Amber Vial, -20°C Freezer, Under inert atmosphere
Solubility.:Chloroform, DCM, Ethyl Acetate, Ethanol

Purity/Quality:

99% ^*data from raw suppliers

(2E,4E)-3-Methyl-5-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)-2,4-pentadienenitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses (2E,4E)-3-Methyl-5-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)-2,4-pentadienenitrile is an intermediate in the synthesis of Vitamin A2 series and isomers of Retinal (R240000) for the potential use in vision restoration and reconstitution treatments.

Technology Process of (2E,4E)-3-Methyl-5-(2,6,6-triMethyl-1,3-cyclohexadien-1-yl)-2,4-pentadienenitrile

There total 2 articles about (2E,4E)-3-Methyl-5-(2,6,6-triMethyl-1,3-cyclohexadien-1-yl)-2,4-pentadienenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 14398-35-7
(3E)-4-(2,6,6-trimethylcyclohexa-1,3-dien-1-yl)but-3-en-2-one

: 21658-95-7
diisopropyl (cyanomethyl)phosphonate

: 20109-91-5
(2E,4E)-3-methyl-5-(2,6,6-trimethyl-1,3-cyclohexadienyl)-2,4-pentanedienenitrile

Guidance literature:: diisopropyl (cyanomethyl)phosphonate; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.5h;

(3E)-4-(2,6,6-trimethylcyclohexa-1,3-dien-1-yl)but-3-en-2-one; In tetrahydrofuran; at 0 - 20 ℃; for 16h; Further stages.;
DOI:10.1248/cpb.56.112

Reference yield:

: 20109-91-5
(2E,4E)-3-methyl-5-(2,6,6-trimethyl-1,3-cyclohexadienyl)-2,4-pentanedienenitrile

Guidance literature:: Dehydro-β-ionon (XVII), Cyanessigsaeure;

Reference yield: 88.0%

: 20109-91-5
(2E,4E)-3-methyl-5-(2,6,6-trimethyl-1,3-cyclohexadienyl)-2,4-pentanedienenitrile

: 25528-87-4
(2E,4E)-3-methyl-5-(2,6,6-trimethyl-1,3-cyclohexadienyl)-2,4-pentadienal

Guidance literature:: (2E,4E)-3-methyl-5-(2,6,6-trimethyl-1,3-cyclohexadienyl)-2,4-pentanedienenitrile; With diisobutylaluminium hydride; In hexane; dichloromethane; at 0 ℃; for 0.5h;

With water; silica gel; In hexane; dichloromethane; for 1h; Further stages.;
DOI:10.1248/cpb.56.112