2-{5-tert-Butoxycarbonyl-2-[(tert-butoxycarbonyl-phenethyl-amino)-methyl]-phenylamino}-succinic acid dimethyl ester

Base Information

Chemical Name:2-{5-tert-Butoxycarbonyl-2-[(tert-butoxycarbonyl-phenethyl-amino)-methyl]-phenylamino}-succinic acid dimethyl ester
CAS No.:147290-86-6
Molecular Formula:C₃₁H₄₂N₂O₈
Molecular Weight:570.683
Hs Code.:

Synonyms:2-{5-tert-Butoxycarbonyl-2-[(tert-butoxycarbonyl-phenethyl-amino)-methyl]-phenylamino}-succinic acid dimethyl ester

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Chemical Property of 2-{5-tert-Butoxycarbonyl-2-[(tert-butoxycarbonyl-phenethyl-amino)-methyl]-phenylamino}-succinic acid dimethyl ester

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Technology Process of 2-{5-tert-Butoxycarbonyl-2-[(tert-butoxycarbonyl-phenethyl-amino)-methyl]-phenylamino}-succinic acid dimethyl ester

There total 7 articles about 2-{5-tert-Butoxycarbonyl-2-[(tert-butoxycarbonyl-phenethyl-amino)-methyl]-phenylamino}-succinic acid dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 161014-58-0
(Z)-2-{5-tert-Butoxycarbonyl-2-[(tert-butoxycarbonyl-phenethyl-amino)-methyl]-phenylamino}-but-2-enedioic acid dimethyl ester

: 147290-86-6
2-{5-tert-Butoxycarbonyl-2-[(tert-butoxycarbonyl-phenethyl-amino)-methyl]-phenylamino}-succinic acid dimethyl ester

Guidance literature:: With hydrogen; palladium on activated charcoal;
DOI:10.1021/ja00072a058

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 147290-86-6
2-{5-tert-Butoxycarbonyl-2-[(tert-butoxycarbonyl-phenethyl-amino)-methyl]-phenylamino}-succinic acid dimethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 85 percent

2: 80 percent / H₂ / 10percent Pd/C

3: 80 percent

4: 98 percent / H₂ / 10percent Pd/C

With hydrogen; palladium on activated charcoal;
DOI:10.1021/ja00072a058

Reference yield:

: 65276-90-6
2-nitro-4-(tert-butoxycarbonyl)benzyl bromide

: 147290-86-6
2-{5-tert-Butoxycarbonyl-2-[(tert-butoxycarbonyl-phenethyl-amino)-methyl]-phenylamino}-succinic acid dimethyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 90 percent

2: 85 percent

3: 80 percent / H₂ / 10percent Pd/C

4: 80 percent

5: 98 percent / H₂ / 10percent Pd/C

With hydrogen; palladium on activated charcoal;
DOI:10.1021/ja00072a058