(E)-N'-(3-(1-benzoyl-1H-indol-3-yl)acryloyl)-N'-isopropylbenzohydrazide

Base Information

Chemical Name:(E)-N'-(3-(1-benzoyl-1H-indol-3-yl)acryloyl)-N'-isopropylbenzohydrazide
CAS No.:1407499-70-0
Molecular Formula:C₂₈H₂₅N₃O₃
Molecular Weight:451.525
Hs Code.:

Synonyms:(E)-N'-(3-(1-benzoyl-1H-indol-3-yl)acryloyl)-N'-isopropylbenzohydrazide

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Chemical Property of (E)-N'-(3-(1-benzoyl-1H-indol-3-yl)acryloyl)-N'-isopropylbenzohydrazide

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Technology Process of (E)-N'-(3-(1-benzoyl-1H-indol-3-yl)acryloyl)-N'-isopropylbenzohydrazide

There total 5 articles about (E)-N'-(3-(1-benzoyl-1H-indol-3-yl)acryloyl)-N'-isopropylbenzohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 1407499-60-8
(E)-N'-(3-(1H-indol-3-yl)acryloyl)-N'-isopropylbenzohydrazide

: 98-88-4
benzoyl chloride

: 1407499-70-0
(E)-N'-(3-(1-benzoyl-1H-indol-3-yl)acryloyl)-N'-isopropylbenzohydrazide

Guidance literature:: With dmap; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 24h;

Reference yield:

: 3408-21-7
1-benzoyl-2-isopropylhydrazine

: 1407499-70-0
(E)-N'-(3-(1-benzoyl-1H-indol-3-yl)acryloyl)-N'-isopropylbenzohydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 12 h / 20 °C

2: N-ethyl-N,N-diisopropylamine; dmap / dichloromethane / 24 h / 20 °C

With dmap; N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 1204-06-4,29953-71-7
trans-3-indole-acrylic acid

: 1407499-70-0
(E)-N'-(3-(1-benzoyl-1H-indol-3-yl)acryloyl)-N'-isopropylbenzohydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 12 h / 20 °C

2: N-ethyl-N,N-diisopropylamine; dmap / dichloromethane / 24 h / 20 °C

With dmap; N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In dichloromethane; N,N-dimethyl-formamide;