4-Chloro-6-methyl-2-(piperidin-1-yl)pyrimidine

Base Information

Chemical Name:4-Chloro-6-methyl-2-(piperidin-1-yl)pyrimidine
CAS No.:42487-70-7
Molecular Formula:C₁₀H₁₄ClN₃
Molecular Weight:211.694
Hs Code.:2933990090
DSSTox Substance ID:DTXSID90589793
Wikidata:Q82483379
Mol file:42487-70-7.mol

Synonyms:42487-70-7;4-chloro-6-methyl-2-piperidin-1-ylpyrimidine;4-chloro-6-methyl-2-(piperidin-1-yl)pyrimidine;4-Chloro-6-methyl-2-(1-piperidinyl)pyrimidine;SCHEMBL3409761;DTXSID90589793;XUIPGTGXJXTPAO-UHFFFAOYSA-N;BBL030984;MFCD08361622;STL355118;AKOS000284119;SB43160;VS-10161;DB-106757;CS-0213260;4-chloro-6-methyl-2-piperidin-1-yl-pyrimidine;EN300-1290871;4-Chloro-6-methyl-2-piperidin-1-ylpyrimidine, AldrichCPR

Suppliers and Price of 4-Chloro-6-methyl-2-(piperidin-1-yl)pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-chloro-6-methyl-2-piperidin-1-ylpyrimidine
1g
$ 60.00

Sigma-Aldrich
4-Chloro-6-methyl-2-piperidin-1-ylpyrimidine Aldrich
1g
$ 57.00

Matrix Scientific
4-Chloro-6-methyl-2-piperidin-1-ylpyrimidine
1g
$ 120.00

Matrix Scientific
4-Chloro-6-methyl-2-piperidin-1-ylpyrimidine
0.500g
$ 100.00

ChemBridge Corporation
4-chloro-6-methyl-2-piperidin-1-ylpyrimidine 95%
25 g
$ 178.40

American Custom Chemicals Corporation
4-CHLORO-6-METHYL-2-PIPERIDIN-1-YLPYRIMIDINE 95.00%
5MG
$ 495.86

AK Scientific
4-Chloro-6-methyl-2-(piperidin-1-yl)pyrimidine
1g
$ 124.00

Total 5 raw suppliers

Chemical Property of 4-Chloro-6-methyl-2-(piperidin-1-yl)pyrimidine

Chemical Property:

Vapor Pressure:2.86E-05mmHg at 25°C
Refractive Index:1.559
Boiling Point:356.7°Cat760mmHg
PKA:4.35±0.50(Predicted)
Flash Point:169.6°C
PSA：29.02000
Density:1.2g/cm³
LogP:2.49370
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:211.0876252
Heavy Atom Count:14
Complexity:182

Purity/Quality:

97% ^*data from raw suppliers

4-chloro-6-methyl-2-piperidin-1-ylpyrimidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=NC(=N1)N2CCCCC2)Cl

Technology Process of 4-Chloro-6-methyl-2-(piperidin-1-yl)pyrimidine

There total 3 articles about 4-Chloro-6-methyl-2-(piperidin-1-yl)pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 42487-69-4
6-methyl-2-piperidinopyrimidin-4(3H)-one

: 42487-70-7
4-chloro-6-methyl-2-piperidinopyrimidine

Guidance literature:: With trichlorophosphate; Heating;
DOI:10.1071/CH9842093

Reference yield:

: 94052-13-8
piperidine-1-carboxamidinium sulfate

: 42487-70-7
4-chloro-6-methyl-2-piperidinopyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 46 percent / sodium ethoxide / ethanol / 5 h / Heating

2: 70 percent / phosphoryl chloride / Heating

With sodium ethanolate; trichlorophosphate; In ethanol;
DOI:10.1071/CH9842093