94052-13-8

Upstream product

• 110-89-4 piperidine 
• 867-44-7 S-Methylisothiourea sulfate 

Downstream Products

• 1047-49-0 6-Benzyl-2-piperidin-1-yl-5,6,7,8-tetrahydro-3H-pyrido[4,3-d]pyrimidin-4-one 
• 1028204-40-1 4-dimethylamino-6-phenyl-2-piperidino-pyrimidine 
• 4705-39-9 piperidine-1-carboxamidine 
• 1403989-56-9 6-dimethylamino-4-[(2R)-2-methoxy-2-[(1S,3S,5R,6R,8R)-3,8-bis(4-methoxyphenyl)-2,4,7,9-tetraoxabicyclo[4.4.0]-decan-5-yl]ethyl]-2-(1-piperidyl)pyrimidine 
• 1403989-55-8 6-dimethylamino-4-[(R)-methoxy-[(1S,3S,5R,6R,8R)-3,8-bis(4-methoxyphenyl)-2,4,7,9-tetraoxabicyclo[4.4.0]decan-5-yl]methyl]-2-(1-piperidyl)pyrimidine 
• 1187456-08-1 C₂₃H₂₃Cl₂N₃ 
• 1187455-91-9 C₂₃H₂₁Cl₂N₃ 
• 1187455-82-8 C₂₃H₂₂FN₃ 
• 1187455-99-7 4-(4-fluoro-phenyl)-2-piperidin-1-yl-3,4,5,6-tetrahydro-benzo[h]quinazoline 
• 42487-70-7 4-chloro-6-methyl-2-piperidinopyrimidine 
• 42487-69-4 6-methyl-2-piperidinopyrimidin-4(3H)-one 
• 1350639-43-8 C₆H₄P(C₆H₅)2C₄N₂H₂N(CH₂)5 
• 33080-90-9 2-Piperidino-3,4-dihydro-chinazolon-(4) 
• 14005-51-7 4-phenyl-2-(piperidin-1-yl)quinazoline 

Relevant academic research and scientific papers

Ultrasound-assisted synthesis of substituted guanidines using 1H-pyrazole-1-carboxamidine and S-methylisothiouronium sulfate under solvent-free conditions

We have investigated ultrasound-assisted synthesis of guanidine derivatives using 1H-Pyrazole-1-carboxamidine (PyzCA) and S-substituted isothiouronium sulfate (MeITU). The guanylations of several amines are promoted by ultrasound sonication under solvent-free conditions, and proceed under mild conditions. It is of particular interest that the guanylations do not require bases in most cases.

Synthesis of substituted indole derivatives as a new class of antimalarial agents

A series of substituted indole derivatives were synthesized and evaluated for their in vitro antimalarial activity against P. falciparum. Out of the 24 compounds synthesized six compounds have shown MIC of 1 μg/mL. These compounds are in vitro several fol