94052-13-8Relevant academic research and scientific papers
Ultrasound-assisted synthesis of substituted guanidines using 1H-pyrazole-1-carboxamidine and S-methylisothiouronium sulfate under solvent-free conditions
Fujita, Mitsue,Furusho, Yoshio
, p. 4339 - 4342 (2018/07/06)
We have investigated ultrasound-assisted synthesis of guanidine derivatives using 1H-Pyrazole-1-carboxamidine (PyzCA) and S-substituted isothiouronium sulfate (MeITU). The guanylations of several amines are promoted by ultrasound sonication under solvent-free conditions, and proceed under mild conditions. It is of particular interest that the guanylations do not require bases in most cases.
Synthesis of substituted indole derivatives as a new class of antimalarial agents
Agarwal, Anu,Srivastava, Kumkum,Puri,Chauhan, Prem M.S.
, p. 3133 - 3136 (2007/10/03)
A series of substituted indole derivatives were synthesized and evaluated for their in vitro antimalarial activity against P. falciparum. Out of the 24 compounds synthesized six compounds have shown MIC of 1 μg/mL. These compounds are in vitro several fol
