(2S)-N-{4-[5-[(5-(5-(4-trifluoromethylphenyl)-1,3,4-oxadiazol-2-yl)-2-methoxyphenyl)oxy]pentyl]oxy-5-methoxy-2-nitrobenzoyl}pyrrolidine-2-carboxaldehyde diethylthioacetal

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Chemical Name:(2S)-N-{4-[5-[(5-(5-(4-trifluoromethylphenyl)-1,3,4-oxadiazol-2-yl)-2-methoxyphenyl)oxy]pentyl]oxy-5-methoxy-2-nitrobenzoyl}pyrrolidine-2-carboxaldehyde diethylthioacetal
CAS No.:1251485-80-9
Molecular Formula:C₃₈H₄₃F₃N₄O₈S₂
Molecular Weight:804.909
Hs Code.:

(2S)-N-{4-[5-[(5-(5-(4-trifluoromethylphenyl)-1,3,4-oxadiazol-2-yl)-2-methoxyphenyl)oxy]pentyl]oxy-5-methoxy-2-nitrobenzoyl}pyrrolidine-2-carboxaldehyde diethylthioacetal

Synonyms:(2S)-N-{4-[5-[(5-(5-(4-trifluoromethylphenyl)-1,3,4-oxadiazol-2-yl)-2-methoxyphenyl)oxy]pentyl]oxy-5-methoxy-2-nitrobenzoyl}pyrrolidine-2-carboxaldehyde diethylthioacetal

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Chemical Property of (2S)-N-{4-[5-[(5-(5-(4-trifluoromethylphenyl)-1,3,4-oxadiazol-2-yl)-2-methoxyphenyl)oxy]pentyl]oxy-5-methoxy-2-nitrobenzoyl}pyrrolidine-2-carboxaldehyde diethylthioacetal

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Technology Process of (2S)-N-{4-[5-[(5-(5-(4-trifluoromethylphenyl)-1,3,4-oxadiazol-2-yl)-2-methoxyphenyl)oxy]pentyl]oxy-5-methoxy-2-nitrobenzoyl}pyrrolidine-2-carboxaldehyde diethylthioacetal

There total 1 articles about (2S)-N-{4-[5-[(5-(5-(4-trifluoromethylphenyl)-1,3,4-oxadiazol-2-yl)-2-methoxyphenyl)oxy]pentyl]oxy-5-methoxy-2-nitrobenzoyl}pyrrolidine-2-carboxaldehyde diethylthioacetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 1251485-62-7
2-methoxy-5-(5-(4-(trifluoromethyl)phenyl)-1,3,4-oxadiazol-2-yl)phenol

: 343308-57-6
(2S)-N-[4-(5-bromopentyloxy)-5-methoxy-2-nitrobenzoyl]pyrrolidine-2-carboxaldehyde diethyl thioacetal

: 1251485-80-9
(2S)-N-{4-[5-[(5-(5-(4-trifluoromethylphenyl)-1,3,4-oxadiazol-2-yl)-2-methoxyphenyl)oxy]pentyl]oxy-5-methoxy-2-nitrobenzoyl}pyrrolidine-2-carboxaldehyde diethylthioacetal

Guidance literature:: With potassium carbonate; In acetone; for 24h; Reflux;
DOI:10.1016/j.bmc.2010.07.067

Reference yield:

: 1251485-80-9
(2S)-N-{4-[5-[(5-(5-(4-trifluoromethylphenyl)-1,3,4-oxadiazol-2-yl)-2-methoxyphenyl)oxy]pentyl]oxy-5-methoxy-2-nitrobenzoyl}pyrrolidine-2-carboxaldehyde diethylthioacetal

: C₃₈H₄₅F₃N₄O₆S₂

Guidance literature:: (2S)-N-{4-[5-[(5-(5-(4-trifluoromethylphenyl)-1,3,4-oxadiazol-2-yl)-2-methoxyphenyl)oxy]pentyl]oxy-5-methoxy-2-nitrobenzoyl}pyrrolidine-2-carboxaldehyde diethylthioacetal; With tin(II) chloride dihdyrate; In methanol; Reflux;

With sodium hydrogencarbonate; In water; pH=8;
DOI:10.1016/j.bmc.2010.07.067