N-(5-allyl-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide

Base Information

Chemical Name:N-(5-allyl-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide
CAS No.:1356998-76-9
Molecular Formula:C₁₈H₂₂FN₃O₂S
Molecular Weight:363.456
Hs Code.:

Synonyms:N-(5-allyl-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide

Suppliers and Price of N-(5-allyl-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(5-allyl-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(5-allyl-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide

There total 3 articles about N-(5-allyl-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1356998-75-8
5-allyl-4-(4-fluorophenyl)-6-isopropyl-N-methylpyrimidin-2-amine

: 124-63-0
methanesulfonyl chloride

: 1356998-76-9
N-(5-allyl-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide

Guidance literature:: With triethylamine; In dichloromethane; at -5 ℃; for 17h; Inert atmosphere;

Reference yield:

: 114433-94-2
1-(4-Fluorophenyl)-3-isopropylpropan-1,3-dione

: 1356998-76-9
N-(5-allyl-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / acetone / 4.17 h / 20 °C

2: sodium hydride / tetrahydrofuran; mineral oil / 48 h / 25 °C

3: triethylamine / dichloromethane / 17 h / -5 °C / Inert atmosphere

With sodium hydride; potassium carbonate; triethylamine; In tetrahydrofuran; dichloromethane; acetone; mineral oil;

Reference yield:

: 1356998-74-7
2-allyl-1-(4-fluorophenyl)-4-methylpentane-1,3-dione

: 1356998-76-9
N-(5-allyl-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride / tetrahydrofuran; mineral oil / 48 h / 25 °C

2: triethylamine / dichloromethane / 17 h / -5 °C / Inert atmosphere

With sodium hydride; triethylamine; In tetrahydrofuran; dichloromethane; mineral oil;