2-Bromo-3-methylbutanoyl bromide

Base Information

• Chemical Name: 2-Bromo-3-methylbutanoyl bromide
• CAS No.: 26464-05-1
• Molecular Formula: C5H8Br2O
• Molecular Weight: 243.926
• Hs Code.: 2915900090
• European Community (EC) Number: 247-719-8
• DSSTox Substance ID: DTXSID60949345
• Nikkaji Number: J136.581I
• Mol file: 26464-05-1.mol

Synonyms:Butyrylbromide, 2-bromo-3-methyl- (6CI,8CI);2-Bromo-3-methylbutanoyl bromide;2-Bromo-3-methylbutyryl bromide;a-Bromoisovaleryl bromide;

Chemical Property of 2-Bromo-3-methylbutanoyl bromide

Chemical Property:

• Appearance/Colour: Clear colourless to slightly yellow liquid
• Vapor Pressure: 0.548mmHg at 25°C
• Melting Point: < 0°C
• Refractive Index: 1.512
• Boiling Point: 190.2 °C at 760 mmHg
• Flash Point: 61.5 °C
• PSA: 17.07000
• Density: 1.802 g/cm³
• LogP: 2.32740
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 243.89214
• Heavy Atom Count: 8
• Complexity: 90.4

Purity/Quality:

99% ^*data from raw suppliers

2-Bromo-3-methylbutyrylbromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)C(C(=O)Br)Br

Technology Process of 2-Bromo-3-methylbutanoyl bromide

There total 4 articles about 2-Bromo-3-methylbutanoyl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-methylbutyric acid (503-74-2) → 2-bromo-3-methyl-butyryl bromide (26464-05-1)

Guidance literature:

With phosphorus; bromine;

Reference yield:

Ethyl isovalerate (108-64-5) → ethyl bromide (74-96-4) + 2-bromo-3-methyl-butyryl bromide (26464-05-1)

Guidance literature:

With phosphorus; bromine;

DOI:10.1002/ardp.19532860205

Reference yield:

→ 2-bromo-3-methyl-butyryl bromide (26464-05-1)

Guidance literature:

upstream raw materials:

3-methylbutyric acid

Ethyl isovalerate

Downstream raw materials:

N-[N-(α-bromo-isovaleryl)-glycyl]-glycine

2-bromo-1-(4-bromophenyl)-3-methylbutan-1-one

2-chloro-1-(2-hydroxy-5-methyl-phenyl)-3-methyl-butan-1-one

4-(α-bromo-isovaleryl)-1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one