2,6-bis[bis(6-pivalamide-2-pyridylmethyl)aminomethyl]-4-nitrophenol

Base Information

• Chemical Name: 2,6-bis[bis(6-pivalamide-2-pyridylmethyl)aminomethyl]-4-nitrophenol
• CAS No.: 1136010-65-5
• Molecular Formula: C₅₂H₆₇N₁₁O₇
• Molecular Weight: 958.173
• Mol file: 1136010-65-5.mol

Synonyms:2,6-bis[bis(6-pivalamide-2-pyridylmethyl)aminomethyl]-4-nitrophenol

Chemical Property of 2,6-bis[bis(6-pivalamide-2-pyridylmethyl)aminomethyl]-4-nitrophenol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,6-bis[bis(6-pivalamide-2-pyridylmethyl)aminomethyl]-4-nitrophenol

There total 1 articles about 2,6-bis[bis(6-pivalamide-2-pyridylmethyl)aminomethyl]-4-nitrophenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.9%

1,3-bis(bromomethyl)-4-nitrophenol (98437-49-1) + N,N'-(6,6'-azanediylbis(methylene)bis(pyridine-6,2-diyl))bis(2,2-dimethylpropanamide) (831195-46-1) → 2,6-bis[bis(6-pivalamide-2-pyridylmethyl)aminomethyl]-4-nitrophenol (1136010-65-5)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 20 ℃; for 72h;

DOI:10.1039/b711802c

Reference yield: 58.7%

2,6-bis[bis(6-pivalamide-2-pyridylmethyl)aminomethyl]-4-nitrophenol (1136010-65-5) → 2,6-bis[bis(6-pivalamido-2-pyridylmethyl)amino-methyl]-4-aminophenol (1009044-49-8)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; at 45 ℃; under 760.051 Torr;

DOI:10.1039/b711802c

upstream raw materials:

1,3-bis(bromomethyl)-4-nitrophenol

N,N'-(6,6'-azanediylbis(methylene)bis(pyridine-6,2-diyl))bis(2,2-dimethylpropanamide)

Downstream raw materials:

2,6-bis[bis(6-pivalamido-2-pyridylmethyl)amino-methyl]-4-aminophenol