4-{1-(4-chlorophenyl)-2,2,2-trifluoro-1-[(trimethylsilyl)-oxy]ethyl}aniline

Base Information

Chemical Name:4-{1-(4-chlorophenyl)-2,2,2-trifluoro-1-[(trimethylsilyl)-oxy]ethyl}aniline
CAS No.:1207469-07-5
Molecular Formula:C₁₇H₁₉ClF₃NOSi
Molecular Weight:373.878
Hs Code.:

Synonyms:4-{1-(4-chlorophenyl)-2,2,2-trifluoro-1-[(trimethylsilyl)-oxy]ethyl}aniline

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Chemical Property of 4-{1-(4-chlorophenyl)-2,2,2-trifluoro-1-[(trimethylsilyl)-oxy]ethyl}aniline

Chemical Property:

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Technology Process of 4-{1-(4-chlorophenyl)-2,2,2-trifluoro-1-[(trimethylsilyl)-oxy]ethyl}aniline

There total 1 articles about 4-{1-(4-chlorophenyl)-2,2,2-trifluoro-1-[(trimethylsilyl)-oxy]ethyl}aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1207471-78-0
[1-(4-chlorophenyl)-2,2,2-trifluoro-1-(4-nitrophenyl)-ethoxy]-(trimethyl)silane

: 1207469-07-5
4-{1-(4-chlorophenyl)-2,2,2-trifluoro-1-[(trimethylsilyl)-oxy]ethyl}aniline

Guidance literature:: [1-(4-chlorophenyl)-2,2,2-trifluoro-1-(4-nitrophenyl)-ethoxy]-(trimethyl)silane; With sodium tetrahydroborate; nickel(II) chloride hexahydrate; In methanol; Cooling with ice;

With ammonia; water; In ethyl acetate;

Reference yield: 47.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 1207469-07-5
4-{1-(4-chlorophenyl)-2,2,2-trifluoro-1-[(trimethylsilyl)-oxy]ethyl}aniline

: 1207471-79-1
tert-butyl {4-[1-(4-chlorophenyl)-2,2,2-trifluoro-1-hydroxyethyl]-phenyl}-carbamate

Guidance literature:: di-tert-butyl dicarbonate; 4-{1-(4-chlorophenyl)-2,2,2-trifluoro-1-[(trimethylsilyl)-oxy]ethyl}aniline; With dmap; triethylamine; In tetrahydrofuran; at 20 ℃;

With tetrabutyl ammonium fluoride; In tetrahydrofuran; for 5h;

With water; ammonium chloride; In tetrahydrofuran;