3-Ethylpyridine-2-carboxylic acid

Base Information

Chemical Name:3-Ethylpyridine-2-carboxylic acid
CAS No.:4116-88-5
Molecular Formula:C8H9 N O2
Molecular Weight:151.165
Hs Code.:2933399090
DSSTox Substance ID:DTXSID60591222
Wikidata:Q82484948
Mol file:4116-88-5.mol

Synonyms:4116-88-5;3-Ethylpyridine-2-carboxylic acid;3-Ethylpicolinic acid;3-Ethylpicolinicacid;Picolinic acid, 3-ethyl- (6CI,7CI,8CI);Athyl-pyridinmonocarbonsaure;SCHEMBL353589;ethyl 2-pyridinecarboxylic acid;DTXSID60591222;INTNEELQXPKMNM-UHFFFAOYSA-N;DA-23623;CS-0124018

Suppliers and Price of 3-Ethylpyridine-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-Ethylpicolinicacid 97%
1g
$ 842.00

Total 6 raw suppliers

Chemical Property of 3-Ethylpyridine-2-carboxylic acid

Chemical Property:

Melting Point:72-73 °C
Boiling Point:294.3±20.0 °C(Predicted)
PKA:1.10±0.50(Predicted)
PSA：50.19000
Density:1.180±0.06 g/cm3(Predicted)
LogP:1.34220
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:151.063328530
Heavy Atom Count:11
Complexity:147

Purity/Quality:

NLT 98% ^*data from raw suppliers

3-Ethylpicolinicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCC1=C(N=CC=C1)C(=O)O

Technology Process of 3-Ethylpyridine-2-carboxylic acid

There total 10 articles about 3-Ethylpyridine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1150617-86-9
methyl 3-ethylpicolinate

: 4116-88-5
3-ethylpicolinic acid

Guidance literature:: methyl 3-ethylpicolinate; With water; lithium hydroxide; In tetrahydrofuran; methanol; at 20 ℃; for 624h;

With hydrogenchloride; In 1,4-dioxane;

Reference yield:

: 157865-84-4
methyl 3-(trifluoromethylsulfonyloxy)-pyridine-2-carboxylate

: 4116-88-5
3-ethylpicolinic acid

Guidance literature:: Multi-step reaction with 3 steps

1: lithium chloride / trans-bis(triphenylphosphine)palladium dichloride / N,N-dimethyl-formamide / 4 h / 100 °C

2: hydrogen / palladium 10% on activated carbon / ethanol / 1 h / 20 °C

3: water; lithium hydroxide / tetrahydrofuran; methanol / 72 h / 20 °C

With water; hydrogen; lithium chloride; lithium hydroxide; trans-bis(triphenylphosphine)palladium dichloride; palladium 10% on activated carbon; In tetrahydrofuran; methanol; ethanol; N,N-dimethyl-formamide;

Reference yield:

: 62733-99-7
methyl 3-hydroxypicolinate

: 4116-88-5
3-ethylpicolinic acid

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine / dichloromethane / 2 h / 0 - 20 °C

2: lithium chloride / trans-bis(triphenylphosphine)palladium dichloride / N,N-dimethyl-formamide / 4 h / 100 °C

3: hydrogen / palladium 10% on activated carbon / ethanol / 1 h / 20 °C

4: water; lithium hydroxide / tetrahydrofuran; methanol / 72 h / 20 °C

With water; hydrogen; triethylamine; lithium chloride; lithium hydroxide; trans-bis(triphenylphosphine)palladium dichloride; palladium 10% on activated carbon; In tetrahydrofuran; methanol; ethanol; dichloromethane; N,N-dimethyl-formamide;