C₂₈H₂₅NO₂

Base Information

• Chemical Name: C₂₈H₂₅NO₂
• CAS No.: 1026643-43-5
• Molecular Formula: C₂₈H₂₅NO₂
• Molecular Weight: 407.512
• Mol file: 1026643-43-5.mol

Synonyms:C₂₈H₂₅NO₂

Chemical Property of C₂₈H₂₅NO₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₂₈H₂₅NO₂

There total 7 articles about C₂₈H₂₅NO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C35H31NO2 (934292-90-7) → C28H25NO2 (1026643-43-5)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethyl acetate; for 14h; under 760.051 Torr;

DOI:10.1021/jo062083t

Reference yield:

C30H28O3 (934292-40-7) → C28H25NO2 (1026643-43-5)

Guidance literature:

Multi-step reaction with 4 steps

1: trifluoroacetic acid

2: oxalyl chloride / dimethylformamide; CH₂Cl₂ / 5 h / 20 °C

3: 79 percent / triethylamine / CH₂Cl₂ / 14 h / 20 °C

4: hydrogen / palladium on carbon / ethyl acetate / 14 h / 760.05 Torr

With oxalyl dichloride; hydrogen; triethylamine; trifluoroacetic acid; palladium on activated charcoal; In dichloromethane; ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1021/jo062083t

Reference yield:

tert-butyl 5-(benzyloxy)-2-iodobenzoate (934292-32-7) → C28H25NO2 (1026643-43-5)

Guidance literature:

Multi-step reaction with 5 steps

1: K₃PO₄; 2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl / Pd₂(dba)3

2: trifluoroacetic acid

3: oxalyl chloride / dimethylformamide; CH₂Cl₂ / 5 h / 20 °C

4: 79 percent / triethylamine / CH₂Cl₂ / 14 h / 20 °C

5: hydrogen / palladium on carbon / ethyl acetate / 14 h / 760.05 Torr

With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; oxalyl dichloride; hydrogen; triethylamine; trifluoroacetic acid; palladium on activated charcoal; tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; In dichloromethane; ethyl acetate; N,N-dimethyl-formamide; 1: Suzuki coupling;

DOI:10.1021/jo062083t

upstream raw materials:

C₃₅H₃₁NO₂

C₃₀H₂₈O₃

tert-butyl 5-(benzyloxy)-2-iodobenzoate

C₂₆H₂₀O₃