iodoacetic acid 5-isopropoxy-2-(4-isopropoxy-3-methoxy-phenylethynyl)-4-methoxy-phenyl ester

Base Information

Chemical Name:iodoacetic acid 5-isopropoxy-2-(4-isopropoxy-3-methoxy-phenylethynyl)-4-methoxy-phenyl ester
CAS No.:200941-19-1
Molecular Formula:C₂₄H₂₇IO₆
Molecular Weight:538.379
Hs Code.:

Synonyms:iodoacetic acid 5-isopropoxy-2-(4-isopropoxy-3-methoxy-phenylethynyl)-4-methoxy-phenyl ester

Suppliers and Price of iodoacetic acid 5-isopropoxy-2-(4-isopropoxy-3-methoxy-phenylethynyl)-4-methoxy-phenyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of iodoacetic acid 5-isopropoxy-2-(4-isopropoxy-3-methoxy-phenylethynyl)-4-methoxy-phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of iodoacetic acid 5-isopropoxy-2-(4-isopropoxy-3-methoxy-phenylethynyl)-4-methoxy-phenyl ester

There total 10 articles about iodoacetic acid 5-isopropoxy-2-(4-isopropoxy-3-methoxy-phenylethynyl)-4-methoxy-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 64-69-7
Iodoacetic acid

: 200941-18-0
5-Isopropoxy-2-(4-isopropoxy-3-methoxy-phenylethynyl)-4-methoxy-phenol

: 200941-19-1
iodoacetic acid 5-isopropoxy-2-(4-isopropoxy-3-methoxy-phenylethynyl)-4-methoxy-phenyl ester

Guidance literature:: With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 18 ℃; for 3h;
DOI:10.1039/a705874h

Reference yield: 97.0%

: 200941-19-1
iodoacetic acid 5-isopropoxy-2-(4-isopropoxy-3-methoxy-phenylethynyl)-4-methoxy-phenyl ester

Guidance literature:

Reference yield:

: 621-59-0
isovanillin

: 200941-19-1
iodoacetic acid 5-isopropoxy-2-(4-isopropoxy-3-methoxy-phenylethynyl)-4-methoxy-phenyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: K₂CO₃ / dimethylformamide / 19 h / 18 °C

2: 93 percent / AgOCOCF₃, I₂ / CHCl₃ / 7 h / Heating

3: 1.) BuLi, ZnCl₂ / 2.) Pd(PPh₃)4 / 1.) THF, -78 deg C, 0.83 h; -78 to 18 deg C, 1 h, 2.) 18 deg C, 4 h

4: MCPBA, KHCO₃ / CH₂Cl₂ / 1 h / 18 °C

5: NH₃ / methanol / 1 h / 18 °C

6: 97 percent / DCC, DMAP / CH₂Cl₂ / 3 h / 18 °C

With dmap; n-butyllithium; ammonia; iodine; silver trifluoroacetate; potassium carbonate; potassium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; dicyclohexyl-carbodiimide; zinc(II) chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In methanol; dichloromethane; chloroform; N,N-dimethyl-formamide;
DOI:10.1039/a705874h