C₂₂H₂₇BrO₃

Base Information

• Chemical Name: C₂₂H₂₇BrO₃
• CAS No.: 1322705-84-9
• Molecular Formula: C₂₂H₂₇BrO₃
• Molecular Weight: 419.359
• Mol file: 1322705-84-9.mol

Synonyms:C₂₂H₂₇BrO₃

Chemical Property of C₂₂H₂₇BrO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₂H₂₇BrO₃

There total 8 articles about C₂₂H₂₇BrO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

C22H27BrO3 (1322705-96-3) → C22H27BrO3 (1322705-84-9)

Guidance literature:

In 1,2-dichloro-benzene; at 250 ℃; for 3h; Microwave irradiation; Inert atmosphere;

DOI:10.1002/anie.201101842

Reference yield:

(R)-4,4,7a-trimethyl-5,6,7,7a-tetrahydro-1H-inden-2(4H)-one → C22H27BrO3 (1322705-84-9)

Guidance literature:

Multi-step reaction with 5 steps

1.1: acetonitrile; acetone / 22.5 h / Irradiation; quartz test tubes

1.2: 0.5 h

2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 40 °C / Inert atmosphere

3.1: sodium t-butanolate / bis(tri-t-butylphosphine)palladium⁽⁰⁾ / 7.5 h / 120 °C / Inert atmosphere; microwave

4.1: bromine / chloroform

5.1: 1,2-dichloro-benzene / 3 h / 250 °C / Inert atmosphere; microwave

With tetrabutyl ammonium fluoride; bromine; sodium t-butanolate; bis(tri-t-butylphosphine)palladium⁽⁰⁾; In tetrahydrofuran; chloroform; 1,2-dichloro-benzene; acetone; acetonitrile;

Reference yield:

C14H20O (1322706-09-1) → C22H27BrO3 (1322705-84-9)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium t-butanolate / bis(tri-t-butylphosphine)palladium⁽⁰⁾ / 7.5 h / 120 °C / Inert atmosphere; microwave

2: bromine / chloroform

3: 1,2-dichloro-benzene / 3 h / 250 °C / Inert atmosphere; microwave

With bromine; sodium t-butanolate; bis(tri-t-butylphosphine)palladium⁽⁰⁾; In chloroform; 1,2-dichloro-benzene;

upstream raw materials:

C₂₂H₂₇BrO₃

allyl 2,6,6-trimethylcyclohex-1-enyl carbonate

C₁₇H₂₈OSi

C₁₄H₂₀O

Downstream raw materials:

C₂₂H₂₉BrO₃

C₂₂H₂₉BrO₃

C₂₃H₃₁BrO₃

C₂₃H₃₃BrO₃