dia-aurantiamide

Base Information

• Chemical Name: dia-aurantiamide
• CAS No.: 150881-04-2
• Molecular Formula: C₂₅H₂₆N₂O₃
• Molecular Weight: 402.493
• Mol file: 150881-04-2.mol

Synonyms:dia-aurantiamide

Chemical Property of dia-aurantiamide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of dia-aurantiamide

There total 3 articles about dia-aurantiamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 8.0%

(R)-2-amino-3-phenylpropanol (5267-64-1) + N-benzoyl-D-phenylalanine (37002-52-1) → N-(N-benzoyl-L-phenylalanyl)-L-phenylalaninol (58115-31-4) + dia-aurantiamide (150881-04-2)

Guidance literature:

With dicyclohexyl-carbodiimide; In dichloromethane; 1.) 0 deg C, 4 h; 2.) room temperature, 2 h;

DOI:10.1016/0031-9422(81)80116-1

Reference yield:

methyl (2S)-2-amino-3-phenylpropanoate (2577-90-4) → dia-aurantiamide (150881-04-2)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlH₄ / tetrahydrofuran

2: 30 percent / N,N'-dicyclohexylcarbodiimide / CH₂Cl₂ / 1.) 0 deg C, 4 h; 2.) room temperature, 2 h

With lithium aluminium tetrahydride; dicyclohexyl-carbodiimide; In tetrahydrofuran; dichloromethane;

DOI:10.1016/0031-9422(81)80116-1

Reference yield:

→ dia-aurantiamide (150881-04-2)

Guidance literature:

p-Nitrophenylester der Saeure 4, Alkohol 2, NaOH;

DOI:10.1016/0040-4020(78)88421-X

upstream raw materials:

(R)-2-amino-3-phenylpropanol

N-benzoyl-D-phenylalanine

methyl (2S)-2-amino-3-phenylpropanoate

Downstream raw materials:

dia-aurantiamide acetate