ethyl 4-{[2-(2'-ethoxybiphenyl-4-yl)-6-fluoro-3-methylquinolin-4-yl]amino}butanoate

Base Information

Chemical Name:ethyl 4-{[2-(2'-ethoxybiphenyl-4-yl)-6-fluoro-3-methylquinolin-4-yl]amino}butanoate
CAS No.:881313-80-0
Molecular Formula:C₃₀H₃₁FN₂O₃
Molecular Weight:486.586
Hs Code.:

Synonyms:ethyl 4-{[2-(2'-ethoxybiphenyl-4-yl)-6-fluoro-3-methylquinolin-4-yl]amino}butanoate

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Chemical Property of ethyl 4-{[2-(2'-ethoxybiphenyl-4-yl)-6-fluoro-3-methylquinolin-4-yl]amino}butanoate

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Technology Process of ethyl 4-{[2-(2'-ethoxybiphenyl-4-yl)-6-fluoro-3-methylquinolin-4-yl]amino}butanoate

There total 1 articles about ethyl 4-{[2-(2'-ethoxybiphenyl-4-yl)-6-fluoro-3-methylquinolin-4-yl]amino}butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 881313-79-7
4-chloro-2-(2'-ethoxybiphenyl-4-yl)-6-fluoro-3-methylquinoline

: 6937-16-2
ethyl γ-aminobutyrate hydrochloride

: 881313-80-0
ethyl 4-{[2-(2'-ethoxybiphenyl-4-yl)-6-fluoro-3-methylquinolin-4-yl]amino}butanoate

Guidance literature:: With triethylamine; tin(IV) chloride; at 130 ℃; for 16h;

Reference yield: 53.0%

: 881313-80-0
ethyl 4-{[2-(2'-ethoxybiphenyl-4-yl)-6-fluoro-3-methylquinolin-4-yl]amino}butanoate

: 881313-81-1
4-{[2-(2'-ethoxybiphenyl-4-yl)-6-fluoro-3-methylquinolin-4-yl]amino}butanoic acid

Guidance literature:: ethyl 4-{[2-(2'-ethoxybiphenyl-4-yl)-6-fluoro-3-methylquinolin-4-yl]amino}butanoate; With lithium hydroxide; water; In tetrahydrofuran; at 20 ℃; for 16h;

With hydrogenchloride; In water; pH=4;