C₂₄H₁₄F₇N₃O₂

Base Information

Chemical Name:C₂₄H₁₄F₇N₃O₂
CAS No.:1581280-33-2
Molecular Formula:C₂₄H₁₄F₇N₃O₂
Molecular Weight:509.383
Hs Code.:

C<sub>24</sub>H<sub>14</sub>F<sub>7</sub>N<sub>3</sub>O<sub>2</sub>

Synonyms:C₂₄H₁₄F₇N₃O₂

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₂₄H₁₄F₇N₃O₂

Chemical Property:

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Technology Process of C₂₄H₁₄F₇N₃O₂

There total 4 articles about C₂₄H₁₄F₇N₃O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1416733-02-2
2-(5-bromopyridin-2-yl)-1-(2,4-difluorophenyl)-2,2-difluoro-1-(pyrimidin-5-yl)ethanol

: 139301-27-2
4-trifluoromethoxyphenylboronic acid

: 1581280-33-2
C₂₄H₁₄F₇N₃O₂

Guidance literature:: With palladium bis[bis(diphenylphosphino)ferrocene] dichloride; potassium carbonate; In 1,4-dioxane; at 75 ℃; for 8h; Inert atmosphere;

Reference yield:

: 294182-06-2
2-(5-bromopyridin-2-yl)-1-(2,4-difluorophenyl)-2,2-difluoroethanone

: 1581280-33-2
C₂₄H₁₄F₇N₃O₂

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / diethyl ether; hexane / 1 h / -78 °C / Inert atmosphere

1.2: 1 h / -78 °C

2.1: potassium carbonate; palladium bis[bis(diphenylphosphino)ferrocene] dichloride / 1,4-dioxane / 8 h / 75 °C / Inert atmosphere

With n-butyllithium; palladium bis[bis(diphenylphosphino)ferrocene] dichloride; potassium carbonate; In 1,4-dioxane; diethyl ether; hexane;

Reference yield:

: 624-28-2
2,5-dibromopyridine

: 1581280-33-2
C₂₄H₁₄F₇N₃O₂

Guidance literature:: Multi-step reaction with 4 steps

1.1: copper / dimethyl sulfoxide / 1 h / 20 °C

1.2: 15 h / 20 °C

2.1: n-butyllithium / diethyl ether; hexane / 3.25 h / -70 - 20 °C

3.1: n-butyllithium / diethyl ether; hexane / 1 h / -78 °C / Inert atmosphere

3.2: 1 h / -78 °C

4.1: potassium carbonate; palladium bis[bis(diphenylphosphino)ferrocene] dichloride / 1,4-dioxane / 8 h / 75 °C / Inert atmosphere

With n-butyllithium; palladium bis[bis(diphenylphosphino)ferrocene] dichloride; copper; potassium carbonate; In 1,4-dioxane; diethyl ether; hexane; dimethyl sulfoxide;