Technology Process of (S,E)-1-((14-iodo-2-(methoxymethoxy)tetradec-3-enyloxy)methyl)-4-methoxybenzene
There total 9 articles about (S,E)-1-((14-iodo-2-(methoxymethoxy)tetradec-3-enyloxy)methyl)-4-methoxybenzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
1H-imidazole; iodine; triphenylphosphine;
In
dichloromethane;
at 0 - 20 ℃;
for 1h;
Inert atmosphere;
DOI:10.1016/j.tetasy.2012.04.004
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1H-imidazole / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere
2: potassium tert-butylate / tetrahydrofuran / 1 h / 0 - 20 °C / Inert atmosphere
3: toluene-4-sulfonic acid / methanol / 1 h / 0 - 20 °C / Inert atmosphere
4: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 6 h / Inert atmosphere; Reflux
5: 1H-imidazole; iodine; triphenylphosphine / dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere
With
1H-imidazole; tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; potassium tert-butylate; iodine; toluene-4-sulfonic acid; triphenylphosphine;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1016/j.tetasy.2012.04.004
- Guidance literature:
-
Multi-step reaction with 5 steps
1: potassium carbonate / methanol / 8 h / 0 °C / Inert atmosphere
2: quinoline; hydrogen / ethyl acetate / 6 h / 20 °C
3: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere
4: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 6 h / Inert atmosphere; Reflux
5: 1H-imidazole; iodine; triphenylphosphine / dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere
With
1H-imidazole; tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; quinoline; hydrogen; iodine; potassium carbonate; N-ethyl-N,N-diisopropylamine; triphenylphosphine;
In
methanol; dichloromethane; ethyl acetate;
DOI:10.1016/j.tetasy.2012.04.004
