Acetic acid 3-acetoxy-2-(2-benzyl-benzoimidazol-1-ylmethoxy)-propyl ester

Base Information

• Chemical Name: Acetic acid 3-acetoxy-2-(2-benzyl-benzoimidazol-1-ylmethoxy)-propyl ester
• CAS No.: 119552-63-5
• Molecular Formula: C₂₂H₂₄N₂O₅
• Molecular Weight: 396.443
• Mol file: 119552-63-5.mol

Synonyms:Acetic acid 3-acetoxy-2-(2-benzyl-benzoimidazol-1-ylmethoxy)-propyl ester

Chemical Property of Acetic acid 3-acetoxy-2-(2-benzyl-benzoimidazol-1-ylmethoxy)-propyl ester

Chemical Property:

Purity/Quality:

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Technology Process of Acetic acid 3-acetoxy-2-(2-benzyl-benzoimidazol-1-ylmethoxy)-propyl ester

There total 1 articles about Acetic acid 3-acetoxy-2-(2-benzyl-benzoimidazol-1-ylmethoxy)-propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

2-(acetoxymethoxy)-1,3-propanediyl diacetate (86357-13-3) + 2-Benzyl-1-trimethylsilanyl-1H-benzoimidazole (119552-56-6) → Acetic acid 3-acetoxy-2-(2-benzyl-benzoimidazol-1-ylmethoxy)-propyl ester (119552-63-5)

Guidance literature:

With chloro-trimethyl-silane; trifluorormethanesulfonic acid; 1,1,1,3,3,3-hexamethyl-disilazane; In acetonitrile;

DOI:10.1007/BF00763529

Reference yield: 90.0%

Acetic acid 3-acetoxy-2-(2-benzyl-benzoimidazol-1-ylmethoxy)-propyl ester (119552-63-5) → 2-(2-Benzyl-benzoimidazol-1-ylmethoxy)-propane-1,3-diol (119552-49-7)

Guidance literature:

With ammonia; In methanol; at 20 ℃; for 24h;

DOI:10.1007/BF00763529

upstream raw materials:

2-(acetoxymethoxy)-1,3-propanediyl diacetate

2-Benzyl-1-trimethylsilanyl-1H-benzoimidazole

Downstream raw materials:

2-(2-Benzyl-benzoimidazol-1-ylmethoxy)-propane-1,3-diol