4-(2-(3H-imidazol-4-yl)pyrrolidine-1-carboxylic acid tert-butyl ester)phenylboonic acid

Base Information

Chemical Name:4-(2-(3H-imidazol-4-yl)pyrrolidine-1-carboxylic acid tert-butyl ester)phenylboonic acid
CAS No.:1256385-77-9
Molecular Formula:C₁₈H₂₄BN₃O₄
Molecular Weight:357.217
Hs Code.:

Synonyms:4-(2-(3H-imidazol-4-yl)pyrrolidine-1-carboxylic acid tert-butyl ester)phenylboonic acid

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Chemical Property of 4-(2-(3H-imidazol-4-yl)pyrrolidine-1-carboxylic acid tert-butyl ester)phenylboonic acid

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Technology Process of 4-(2-(3H-imidazol-4-yl)pyrrolidine-1-carboxylic acid tert-butyl ester)phenylboonic acid

There total 3 articles about 4-(2-(3H-imidazol-4-yl)pyrrolidine-1-carboxylic acid tert-butyl ester)phenylboonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1256385-76-8
2-(2-(4-bromophenyl)-3H-imidazol-4-yl)pyrrolidine-1-carboxylic acid tert-butyl ester

: 73183-34-3
bis(pinacol)diborane

: 1256385-77-9
4-(2-(3H-imidazol-4-yl)pyrrolidine-1-carboxylic acid tert-butyl ester)phenylboonic acid

Guidance literature:: With potassium acetate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; at 100 ℃; for 40h;

Reference yield:

: 102284-41-3,848819-60-3
2-(2-chloroacetyl)pyrrolidine-1-carboxylic acid tert-butyl ester

: 1256385-77-9
4-(2-(3H-imidazol-4-yl)pyrrolidine-1-carboxylic acid tert-butyl ester)phenylboonic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / tetrahydrofuran; water / 10 h / 65 °C

2: potassium acetate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane / 40 h / 100 °C

With potassium acetate; potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; 1,4-dioxane; water;

Reference yield:

: 22265-36-7
4-bromobenzamidine

: 1256385-77-9
4-(2-(3H-imidazol-4-yl)pyrrolidine-1-carboxylic acid tert-butyl ester)phenylboonic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / tetrahydrofuran; water / 10 h / 65 °C

2: potassium acetate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane / 40 h / 100 °C

With potassium acetate; potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; 1,4-dioxane; water;