1,4-bis[5-(hydrazinocarbonylmethyl)thio-4-p-tolyl-1,2,4-triazol-3-yl]butane

Base Information

• Chemical Name: 1,4-bis[5-(hydrazinocarbonylmethyl)thio-4-p-tolyl-1,2,4-triazol-3-yl]butane
• CAS No.: 1266399-88-5
• Molecular Formula: C₂₆H₃₂N₁₀O₂S₂
• Molecular Weight: 580.738
• Mol file: 1266399-88-5.mol

Synonyms:1,4-bis[5-(hydrazinocarbonylmethyl)thio-4-p-tolyl-1,2,4-triazol-3-yl]butane

Chemical Property of 1,4-bis[5-(hydrazinocarbonylmethyl)thio-4-p-tolyl-1,2,4-triazol-3-yl]butane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,4-bis[5-(hydrazinocarbonylmethyl)thio-4-p-tolyl-1,2,4-triazol-3-yl]butane

There total 5 articles about 1,4-bis[5-(hydrazinocarbonylmethyl)thio-4-p-tolyl-1,2,4-triazol-3-yl]butane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

1,4-bis-[5-(carbethoxymethyl)thio-4-(p-tolyl)-1,2,4-triazol-3-yl]butane (1266399-82-9) → 1,4-bis[5-(hydrazinocarbonylmethyl)thio-4-p-tolyl-1,2,4-triazol-3-yl]butane (1266399-88-5)

Guidance literature:

With hydrazine; In ethanol; for 8h; Reflux;

DOI:10.1007/s00044-010-9517-9

Reference yield:

1-isothiocyanato-4-methylbenzene (622-59-3) → 1,4-bis[5-(hydrazinocarbonylmethyl)thio-4-p-tolyl-1,2,4-triazol-3-yl]butane (1266399-88-5)

Guidance literature:

Multi-step reaction with 4 steps

1: Reflux

2: Heating; Alkaline conditions

3: acetone / Reflux

4: hydrazine hydrate / ethanol

With hydrazine hydrate; In ethanol; acetone;

DOI:10.1002/ardp.201000177

Reference yield:

C22H24N6S2 (64546-22-1) → 1,4-bis[5-(hydrazinocarbonylmethyl)thio-4-p-tolyl-1,2,4-triazol-3-yl]butane (1266399-88-5)

Guidance literature:

Multi-step reaction with 2 steps

1: acetone / Reflux

2: hydrazine hydrate / ethanol

With hydrazine hydrate; In ethanol; acetone;

DOI:10.1002/ardp.201000177

upstream raw materials:

1,4-bis-[5-(carbethoxymethyl)thio-4-(p-tolyl)-1,2,4-triazol-3-yl]butane

4,4'-di-p-tolyl-1,1'-hexanedioyl-bis-thiosemicarbazide

C₂₂H₂₄N₆S₂

1-isothiocyanato-4-methylbenzene

Downstream raw materials:

1,4-bis[5-(1-oxo-1-(3,5-dimethylpyrazol-1-yl)methyl)thio-4-(p-tolyl)-1,2,4-triazol-3-yl]butane

1,4-bis[5-(5-mercapto-1,3,4-oxadiazol-2-yl-methyl)-thio-4-(p-tolyl)-1,2,4-triazol-3-yl]-butane