1-[(2R)-Butan-2-yl]-4-fluorobenzene

Base Information

Chemical Name:1-[(2R)-Butan-2-yl]-4-fluorobenzene
CAS No.:326879-17-8
Molecular Formula:C₁₀H₁₃F
Molecular Weight:152.212
Hs Code.:
DSSTox Substance ID:DTXSID70572567
Nikkaji Number:J1.438.150C
Wikidata:Q82460952
Mol file:326879-17-8.mol

Synonyms:326879-17-8;1-[(2R)-Butan-2-yl]-4-fluorobenzene;Benzene,1-fluoro-4-[(1R)-1-methylpropyl]-(9CI);SCHEMBL16234256;DTXSID70572567

Suppliers and Price of 1-[(2R)-Butan-2-yl]-4-fluorobenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-[(2R)-Butan-2-yl]-4-fluorobenzene

Chemical Property:

PSA：0.00000
LogP:3.33920
XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:152.100128577
Heavy Atom Count:11
Complexity:103

Purity/Quality:: 99%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(C)C1=CC=C(C=C1)F
Isomeric SMILES:CC[C@@H](C)C1=CC=C(C=C1)F

Technology Process of 1-[(2R)-Butan-2-yl]-4-fluorobenzene

There total 13 articles about 1-[(2R)-Butan-2-yl]-4-fluorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 598-30-1
sec.-butyllithium

: 460-00-4
1-Bromo-4-fluorobenzene

: 326879-17-8
1-(sec-butyl)-4-fluorobenzene

Guidance literature:: With bis(tri-t-butylphosphine)palladium⁽⁰⁾; water; sodium chloride; In cyclohexane; at 20 ℃; for 0.00555556h; pH=6; Schlenk technique;
DOI:10.1002/anie.201812537

Reference yield: 84.0%

: 1-(but-1-en-2-yl)-4-fluorobenzene

: 7119-14-4
2-(p-Fluorphenyl)-2-buten

: 326879-17-8
(R)-1-(sec-butyl)-4-fluorobenzene

Guidance literature:: With hydrogen; C₂₉H₃₅Cl₂FeN₃O; sodium triethylborohydride; acetonitrile; octadecyl silane; In toluene; at 20 ℃; for 12h; enantioselective reaction; Schlenk technique;
DOI:10.1021/jacs.1c04773

Reference yield: 83.0%

: C₁₃H₂₁FOSi

: 326879-17-8
(S)-1-(sec-butyl)-4-fluorobenzene

Guidance literature:: With C₃₂H₁₂BF₂₄^(1-)*C₄₉H₄₂IrNO₅P⁽¹⁺⁾; hydrogen; In dichloromethane; at 20 ℃; for 2h; under 750.075 Torr; enantioselective reaction;
DOI:10.1039/c8sc05261a