4-Fluorostyrene

Base Information

• Chemical Name: 4-Fluorostyrene
• CAS No.: 405-99-2
• Molecular Formula: C8H7F
• Molecular Weight: 122.142
• Hs Code.: 29036990
• European Community (EC) Number: 206-975-0
• UNII: JE3FH53DP6
• DSSTox Substance ID: DTXSID50193512
• Nikkaji Number: J213.663E
• Wikidata: Q72477031
• Mol file: 405-99-2.mol

Synonyms:4-Fluorostyrene;405-99-2;1-Fluoro-4-vinylbenzene;p-Fluorostyrene;1-ethenyl-4-fluorobenzene;Benzene, 1-ethenyl-4-fluoro-;Styrene, p-fluoro-;para-Fluorostyrene;EINECS 206-975-0;MFCD00000361;1-fluoro-4-vinyl-benzene;4-fluoro-styrene;p-vinylfluorobenzene;4-fluoro-1-vinylbenzene;1-fluoro-4-ethenylbenzene;1-Fluoro-4-vinylbenzene #;JE3FH53DP6;SCHEMBL49710;SCHEMBL12112952;AMY8787;DTXSID50193512;BBL102934;CK2549;STL556743;AKOS005256947;PS-9216;BB 0221043;F0461;FT-0618563;EN300-60989;A825191;W-106343;4-Fluorostyrene stabilized with 0.1% tert-butylcatechol;(E)-2-(4-chlorophenyl)-3-(dimethylamino)prop-2-enenitrile;2-Chloro-4-pyridinecarboxylic acid1,1-dimethylEthyl ester;4-Fluorostyrene, 99%, contains tert-butylcatechol as inhibitor;4-FLUOROSTYRENE (CONTAINS TERT-BUTYLCATECHOL AS INHIBITOR)

Chemical Property of 4-Fluorostyrene

Chemical Property:

• Appearance/Colour: clear colorless to very slightly yellow liquid
• Vapor Pressure: 6.17mmHg at 25°C
• Melting Point: -36--33 °C
• Refractive Index: n20/D 1.514(lit.)
• Boiling Point: 145.3 °C at 760 mmHg
• Flash Point: 31.3 °C
• PSA: 0.00000
• Density: 1.021 g/cm³
• LogP: 2.46870
• Storage Temp.: 2-8°C
• Water Solubility.: Insoluble in water.
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 122.053178385
• Heavy Atom Count: 9
• Complexity: 90.7

Purity/Quality:

99% ^*data from raw suppliers

4-Fluorostyrene ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F, Xi
• Hazard Codes: F,Xi
• Statements: 10-36/37/38
• Safety Statements: 23-24/25-37/39-26-16

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C=CC1=CC=C(C=C1)F
• Uses: 4-Fluorostyrene, is an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

Technology Process of 4-Fluorostyrene

There total 69 articles about 4-Fluorostyrene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1-(1,2-dibromoethyl)-4-fluorobenzene (350-35-6) → para-fluorostyrene (405-99-2)

Guidance literature:

at 20 ℃; for 0.05h; chemoselective reaction;

DOI:10.5012/jkcs.2018.62.4.275

Reference yield: 94.0%

rac-2-(4-fluorophenyl)thiirane (18511-64-3) → para-fluorostyrene (405-99-2)

Guidance literature:

With molybdenum(V) chloride; zinc; In tetrahydrofuran; at 20 ℃; for 0.5h;

DOI:10.1080/17415993.2021.1994573

Reference yield: 94.0%

4-fluorostyrene oxide (18511-62-1,53631-23-5,134356-73-3,134356-74-4) → para-fluorostyrene (405-99-2)

Guidance literature:

With carbon monoxide; In water; at 27 ℃; for 12h; under 760.051 Torr; chemoselective reaction;

DOI:10.1002/chem.201001387

upstream raw materials:

(2-bromoethyl)-4-fluorobenzene

2-(4-Fluorophenyl)ethanol

(iodomethyl)triphenylphosphonium iodide

4-fluorobenzaldehyde

Downstream raw materials:

7-(4-fluoro-phenyl)-1,5,6,7-tetrahydro-pyrano[2,3-d]pyrimidine-2,4-dione

1,10-Dibrom<2.2>paracyclophan-1-en

1,9-Dibrom<2.2>paracyclophan-1-en

4'',5'-Bis(4-fluorphenyl)dibenzo<2.2>paracyclophan-1,9-dien-4',5''-dicarbaldehyd

Refernces

• 1、 Hasenbeck, Max,Wech, Felix,Averdunk, Arthur,Becker, Jonathan,Gellrich, Urs. "Indene formation upon borane-induced cyclization of arylallenes, 1,1-carboboration, and retro-hydroboration". supporting information. p. 5518 - 5521. Retrieved 2021/06/12.
• 2、 Jiang, Yi-Min,Wu, Shao-Fen,Yan, Hong,Ye, Ke-Yin,Yu, Yi,Yuan, Yaofeng. "Electrochemical fluorosulfonylation of styrenes". supporting information. p. 11481 - 11484. Retrieved 2021/11/16.