ethyl (4-{[5-bromo-3-(1,3-thiazol-2-yl)-1H-indol-1-yl]sulfonyl}-2-methylphenoxy)-acetate

Base Information

Chemical Name:ethyl (4-{[5-bromo-3-(1,3-thiazol-2-yl)-1H-indol-1-yl]sulfonyl}-2-methylphenoxy)-acetate
CAS No.:720713-09-7
Molecular Formula:C₂₂H₁₉BrN₂O₅S₂
Molecular Weight:535.439
Hs Code.:

Synonyms:ethyl (4-{[5-bromo-3-(1,3-thiazol-2-yl)-1H-indol-1-yl]sulfonyl}-2-methylphenoxy)-acetate

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Chemical Property of ethyl (4-{[5-bromo-3-(1,3-thiazol-2-yl)-1H-indol-1-yl]sulfonyl}-2-methylphenoxy)-acetate

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Technology Process of ethyl (4-{[5-bromo-3-(1,3-thiazol-2-yl)-1H-indol-1-yl]sulfonyl}-2-methylphenoxy)-acetate

There total 1 articles about ethyl (4-{[5-bromo-3-(1,3-thiazol-2-yl)-1H-indol-1-yl]sulfonyl}-2-methylphenoxy)-acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 720713-08-6
5-bromo-3-(1,3-thiazol-2-yl)-1H-indole

: 91427-62-2
(4-chlorosulfonyl-2-methyl-phenoxy)-acetic acid ethyl ester

: 720713-09-7
ethyl (4-{[5-bromo-3-(1,3-thiazol-2-yl)-1H-indol-1-yl]sulfonyl}-2-methylphenoxy)-acetate

Guidance literature:: With potassium carbonate; In butanone; Heating / reflux;

Reference yield: 82.0%

: 720713-09-7
ethyl (4-{[5-bromo-3-(1,3-thiazol-2-yl)-1H-indol-1-yl]sulfonyl}-2-methylphenoxy)-acetate

: 128796-39-4
4-trifluoromethylphenylboronic acid

: [2-methyl-4-({3-(1,3-thiazol-2-yl)-5-[4-(trifluoromethyl)phenyl]-1H-indol-1-yl}-sulfonyl)phenoxy]acetic acid

Guidance literature:: ethyl (4-{[5-bromo-3-(1,3-thiazol-2-yl)-1H-indol-1-yl]sulfonyl}-2-methylphenoxy)-acetate; 4-trifluoromethylphenylboronic acid; bis-triphenylphosphine-palladium(II) chloride; In DMF (N,N-dimethyl-formamide); at 70 ℃; for 0.5h;

With water; sodium carbonate; In DMF (N,N-dimethyl-formamide); at 100 ℃; for 16h;