91427-62-2

Usage

Uses

Used in Organic Synthesis:
ETHYL [2-METHYL-3-(CHLOROSULFONYL)PHENOXY]ACETATE is used as a synthetic intermediate for the production of various organic compounds. Its reactivity allows it to participate in a range of chemical reactions, such as nucleophilic substitutions, eliminations, and rearrangements, which are crucial for constructing complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, ETHYL [2-METHYL-3-(CHLOROSULFONYL)PHENOXY]ACETATE is utilized as a key building block in the synthesis of pharmaceutical agents. Its ability to form diverse chemical linkages makes it valuable for the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
ETHYL [2-METHYL-3-(CHLOROSULFONYL)PHENOXY]ACETATE also finds application in the agrochemical industry, where it serves as a precursor for the synthesis of various agrochemicals, including pesticides and herbicides. Its involvement in the formation of these compounds contributes to the development of effective solutions for crop protection and management.
Used in Dye and Pigment Industry:
In the dye and pigment industry, ETHYL [2-METHYL-3-(CHLOROSULFONYL)PHENOXY]ACETATE is employed as a starting material for the synthesis of dyes and pigments. Its chemical properties enable the creation of a wide array of colorants used in various applications, such as textiles, plastics, and printing inks.
Used in Research and Development:
ETHYL [2-METHYL-3-(CHLOROSULFONYL)PHENOXY]ACETATE is also used in research and development settings, where it is studied for its potential applications and properties. Scientists and researchers explore its reactivity and behavior in different chemical environments to discover new uses and improve existing processes.

Upstream product

• 93917-68-1 ethyl (2-methylphenoxy)acetate 
• 95-48-7 ortho-cresol 

Downstream Products

• 343322-82-7 ethyl [(4-mercapto-2-methylphenyl)oxy]acetate 
• 637352-74-0 ethyl [4-({butyl[4'-(trifluoromethyl)-1,1'-biphenyl-3-yl]amino}sulfonyl)-2-methylphenoxy]acetate 
• 637352-75-1 ethyl [2-methyl-4-({pentyl[4'-(trifluoromethyl)-1,1'-biphenyl-3-yl]amino}sulfonyl)phenoxy]acetate 
• 637352-76-2 ethyl [4-({(2-cyclopropylethyl)[4'-(trifluoromethyl)-1,1'-biphenyl-3-yl]amino}sulfonyl)-2-methylphenoxy]acetate 
• 637353-26-5 ethyl [4-({butyl[2-methyl-4'-(trifluoromethyl)-1,1'-biphenyl-3-yl]amino}sulfonyl)-2-methylphenoxy]acetate 
• 720713-06-4 ethyl {4-[(5-bromo-3-isopropyl-1H-indol-1-yl)sulfonyl]-2-methylphenoxy}acetate 
• 720713-09-7 ethyl (4-{[5-bromo-3-(1,3-thiazol-2-yl)-1H-indol-1-yl]sulfonyl}-2-methylphenoxy)-acetate 
• 645417-01-2 ethyl {4-[(5-bromo-2,3-dihydro-1H-indol-1-yl)sulfonyl]-2-methylphenoxy}acetate 
• 645417-03-4 ethyl {4-[(5-bromo-3,3-dimethyl-2,3-dihydro-1H-indol-1-yl)sulfonyl]-2-methylphenoxy}acetate 
• 645416-86-0 ethyl {4-[(5-bromo-3-isopropyl-7-methyl-2,3-dihydro-1H-indol-1-yl)sulfonyl]-2-methylphenoxy}acetate 
• 645416-90-6 ethyl {4-[(5-bromo-2,3,7-trimethyl-2,3-dihydro-1H-indol-1-yl)sulfonyl]-2-methyl-phenoxy}acetate 
• 645416-93-9 ethyl {4-[(5-bromo-3,7-dimethyl-2,3-dihydro-1H-indol-1-yl)sulfonyl]-2-methylphenoxy}acetate 
• 638214-20-7 ethyl {[2-methyl-4-({1-[4'-(trifluoromethyl)-3-biphenylyl]ethyl}thio)phenyl]oxy}acetate 
• 56077-47-5 (4-mercapto-2-methyl-phenoxy)-acetic acid methyl ester 

Relevant academic research and scientific papers

Base Catalysis Enables Access to α,α-Difluoroalkylthioethers

A nucleophilic addition reaction of aryl thiols to readily available β,β-difluorostyrenes provides α,α-difluoroalkylthioethers. The reaction proceeds through an unstable anionic intermediate, prone to eliminate fluoride and generate α-fluorovinylthioethers. However, the use of base catalysis overcomes the facile β-fluoride elimination, generating α,α-difluoroalkylthioethers in excellent yields and selectivities.

PPAR-DELTA LIGANDS AND METHODS OF THEIR USE

The disclosure provides compounds, compositions, and methods for modulating PPARδ receptor. In one embodiment, the compounds of the disclosure comprise a tri-substituted thiazole group. The substituent at the 2-position of the thiazole group provides steric bulk to the compounds. The compounds, compositions, and methods may be useful, for example, in the treatment of cancer.

4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs

The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.

4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs

The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.

1,3,5-Trisubstituted aryls as highly selective PPARδ agonists

A series of highly potent and selective PPARδ agonists is described using the known non-selective ligand GW2433 as a structural template. Compound 1 is bioavailable, potent (10 nM), and shows no cross-activity with other PPAR subtypes up to 10 μM, making it a useful tool in studying the biological effects of selective PPARδ activation.

4-((Phenoxyalkyl)thio)-phenoxyacetic acids and analogs

The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.

4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS

The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.

4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS

The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.

Compounds, compositions and treatment of oleoylethanolamide-like modulators of PPARalpha

The present invention provides compounds, compositions, and methods for the treatment of disorders and conditions mediated by PPARα. The invention relates to the surprising discovery that oleoylethanolamide (OEA) is an endogenous high affinity and selecti

COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of the Peroxisome Proliferator-Activated Receptor (PPAR) families, particularly the activity of PPAR.