D-glycero-Pentonic acid, 2,3-dideoxy-2-(1-methylethyl)-, gamma-lactone, (4xi-iota)- (9CI)

Base Information

Chemical Name:D-glycero-Pentonic acid, 2,3-dideoxy-2-(1-methylethyl)-, gamma-lactone, (4xi-iota)- (9CI)
CAS No.:325740-55-4
Molecular Formula:C8H14 O3
Molecular Weight:158.197
Hs Code.:
Mol file:325740-55-4.mol

Synonyms:D-glycero-Pentonic acid, 2,3-dideoxy-2-(1-methylethyl)-, gamma-lactone, (4xi-iota)- (9CI)

Suppliers and Price of D-glycero-Pentonic acid, 2,3-dideoxy-2-(1-methylethyl)-, gamma-lactone, (4xi-iota)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of D-glycero-Pentonic acid, 2,3-dideoxy-2-(1-methylethyl)-, gamma-lactone, (4xi-iota)- (9CI)

Chemical Property:

PSA：46.53000
LogP:0.56640

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of D-glycero-Pentonic acid, 2,3-dideoxy-2-(1-methylethyl)-, gamma-lactone, (4xi-iota)- (9CI)

There total 2 articles about D-glycero-Pentonic acid, 2,3-dideoxy-2-(1-methylethyl)-, gamma-lactone, (4xi-iota)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 240821-65-2
(4S)-3-[(2S)-2-(1-methylethyl)-1-oxopent-4-en-1-yl]-4-(phenylmethyl)oxazolidin-2-one

: 325740-55-4,191152-30-4,325740-73-6
(S)-5-Hydroxymethyl-3-isopropyl-dihydro-furan-2-one

Guidance literature:: With osmium(VIII) oxide; 4-methylmorpholine N-oxide; In water; acetone; tert-butyl alcohol;
DOI:10.1016/S0040-4039(00)01794-9

Reference yield:

: 145589-03-3,104266-90-2
(S)-4-benzyl-3-(3-methylbutanoyl)oxazolidin-2-one

: 325740-55-4,191152-30-4,325740-73-6
(S)-5-Hydroxymethyl-3-isopropyl-dihydro-furan-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / LIHMDS / tetrahydrofuran / -78 °C

2: 88 percent / OsO₄; NMMO / 2-methyl-propan-2-ol; acetone; H₂O

With osmium(VIII) oxide; 4-methylmorpholine N-oxide; lithium hexamethyldisilazane; In tetrahydrofuran; water; acetone; tert-butyl alcohol;
DOI:10.1016/S0040-4039(00)01794-9

Reference yield:

: 325740-55-4,191152-30-4,325740-73-6
(S)-5-Hydroxymethyl-3-isopropyl-dihydro-furan-2-one

: 324763-47-5
(2S,4S,5S,7S)-N-(3-amino-2,2-dimethyl-3-oxopropyl)-5-azido-4-hydroxy-2-isopropyl-7-(4-methoxy-3-(methoxypropoxy)benzyl)-8-methylnonanamide

Guidance literature:: Multi-step reaction with 10 steps

1: NaIO₄; RuCl₃*H₂O / CCl₄; acetonitrile; H₂O / 6 h

2: (COCl)2 / dimethylformamide; toluene / 1 h

3: NEt₃ / CH₂Cl₂

4: 100 percent / H₂ / Pd/C / ethyl acetate

5: (COCl)2 / toluene; dimethylformamide / 1 h

6: Mg; BrCH₂CH₂Br / tetrahydrofuran / 20 °C

7: H₂ / [Ru₂Cl₄((S)-BINAP)]NEt₃ / methanol / 40 h / 40 °C / 37503 Torr

8: NEt₃ / CH₂Cl₂

9: 85 percent / NaN₃; 15-crown-6; DMPU

10: 59 percent / 2-OH-pyridine; NEt₃

With 2-hydroxypyridin; 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; ruthenium trichloride; sodium periodate; sodium azide; oxalyl dichloride; 15-crown-6; hydrogen; magnesium; ethylene dibromide; triethylamine; palladium on activated charcoal; [Ru₂Cl₄((S)-BINAP)]NEt₃; In tetrahydrofuran; methanol; tetrachloromethane; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide; toluene; acetonitrile;
DOI:10.1016/S0040-4039(00)01794-9